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      Accumulation of Ascorbic Acid in the Corneal Epithelium

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      Ophthalmic Research

      S. Karger AG

      Ascorbic acid, Rabbit cornea, Rabbit aqueous humour

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          Abstract

          In the aqueous humour and the corneal epithelium of rabbits, the ascorbic acid levels were investigated using the photometric assay with 2,6-dichlorophenolindophenol. After injection of 300 mg/kg body weight of ascorbate, the aqueous humour ascorbic acid levels were slightly elevated, showing the well-known saturation kinetics. In the corneal epithelium the ascorbic acid levels were increased by twice the amount of that of the aqueous humour. The significance of an ascorbic acid therapy in corneal diseases is discussed

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          Author and article information

          Journal
          ORE
          Ophthalmic Res
          10.1159/issn.0030-3747
          Ophthalmic Research
          S. Karger AG
          0030-3747
          1423-0259
          1978
          1978
          03 December 2009
          : 10
          : 3
          : 135-139
          Affiliations
          Department of Ophthalmology (Director: Prof. M. Reim), Faculty of Medicine, Rheinisch-Westfälische Technische Hochschule, Aachen
          Article
          264946 Ophthalmic Res 1978;10:135–139
          10.1159/000264946
          © 1978 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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          Pages: 5
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