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      • Record: found
      • Abstract: found
      • Article: found

      Accumulation of Ascorbic Acid in the Corneal Epithelium

      research-article
      Author(s): , ,
      Publication date (Electronic):
      Journal: Ophthalmic Research
      Publisher: S. Karger AG
      Keywords: Ascorbic acid, Rabbit cornea, Rabbit aqueous humour

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          Abstract

          In the aqueous humour and the corneal epithelium of rabbits, the ascorbic acid levels were investigated using the photometric assay with 2,6-dichlorophenolindophenol. After injection of 300 mg/kg body weight of ascorbate, the aqueous humour ascorbic acid levels were slightly elevated, showing the well-known saturation kinetics. In the corneal epithelium the ascorbic acid levels were increased by twice the amount of that of the aqueous humour. The significance of an ascorbic acid therapy in corneal diseases is discussed

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          Author and article information

          Journal
          Journal ID (publisher-id): ORE
          Journal ID (nlm-ta): Ophthalmic Res
          Journal ID (doi): 10.1159/issn.0030-3747
          Title: Ophthalmic Research
          Publisher: S. Karger AG
          ISSN (Print): 0030-3747
          ISSN (Electronic): 1423-0259
          Publication date Subscription-year: 1978
          Publication date (Print): 1978
          Publication date (Electronic): 03 December 2009
          Volume: 10
          Issue: 3
          Pages: 135-139
          Affiliations
          Department of Ophthalmology (Director: Prof. M. Reim), Faculty of Medicine, Rheinisch-Westfälische Technische Hochschule, Aachen
          Article
          Publisher ID: 264946 Other ID: Ophthalmic Res 1978;10:135–139
          DOI: 10.1159/000264946
          SO-VID: 445674c8-9262-41b6-b9e6-365aca1ad155
          Copyright © © 1978 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Date received : 08 March 1978
          Date accepted : 01 June 1978
          Page count
          Pages: 5
          Categories
          Subject: Paper

          ScienceOpen disciplines: Vision sciences,Ophthalmology & Optometry,Pathology
          Keywords: Ascorbic acid,Rabbit cornea,Rabbit aqueous humour
          Data availability:
          ScienceOpen disciplines: Vision sciences, Ophthalmology & Optometry, Pathology
          Keywords: Ascorbic acid, Rabbit cornea, Rabbit aqueous humour

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