25
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Physiologic changes of pregnancy: A review of the literature ☆☆

      review-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Throughout pregnancy, the body undergoes a variety of physiologic changes. The cutaneous findings can be most noticeable and often worrisome to both physicians and patients. Obstetricians and dermatologists must be able to differentiate between changes that are benign and those that may be pathologic. Most physicians recognize benign changes that are commonly described in literature such as hyperpigmentation, melasma, striae gravidarum, and telogen effluvium; however, they may be unaware of changes that tend to be less frequently discussed. This comprehensive review provides a broad overview of the physiologic cutaneous changes that occur during pregnancy as described in the literature over the past 10 years.

          Related collections

          Most cited references24

          • Record: found
          • Abstract: found
          • Article: not found

          Physiological changes associated with the menstrual cycle: a review.

          The cyclic hormonal changes that regulate the menstrual cycle are a significant biological influence on the female body, one with both physical and emotional ramifications. Menstruation is governed by tightly orchestrated changes in the levels of ovarian estrogen and progesterone, which produce varying responses in diverse tissues and organs. The skin, the largest organ in the body, is replete with estrogen receptors (in both dermis and epidermis) and to a lesser extent, progesterone receptors. Cyclically fluctuating levels of estrogen and progesterone influence numerous characteristics of the epidermis, including skin surface lipid secretion and sebum production, skin thickness, fat deposition, skin hydration, and barrier function. Dermal collagen content, which contributes to skin elasticity and resistance to wrinkling, is also influenced. Interestingly, estrogen levels also influence skin pigmentation and UV susceptibility, as well as resident microflora. In addition, changing hormone levels across the menstrual cycle produce measurable variations in immune function and disease susceptibility. An understanding of the profound influence that fluctuating estrogen and progesterone levels have on the biological responses of the premenopausal adult woman is critical to optimizing the efficacy of medical therapies in this population.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Systemic alterations and their oral manifestations in pregnant women.

            The aims of this literature review are: to depict the main oral diseases that are related to pregnancy; to clarify some of the possible systemic mechanisms that are associated with these changes; and to address issues about oral care during pregnancy. A woman's organs undergo various physiological, neurological, and hormonal changes during pregnancy. Such changes occur gradually and are essential for the development of the fetus, providing what is needed for tissue formation and establishment of reserves for uterine and fetal life. In turn, the oral cavity shows some events during this period. Among the changes most frequently cited in the literature are pyogenic granuloma, gingivitis, and periodontitis. The inflammation of the periodontal tissues due to the formation of the biofilm increases dramatically in size and severity during the course of a normal pregnancy, even without changes in the amount of biofilm present. In addition, a decrease in salivary pH is observed in pregnant women and may lead to an increased incidence of dental caries in this period.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Lower extremity changes experienced during pregnancy.

              The anatomic and physiologic changes occurring with pregnancy result in a variety of symptoms affecting the lower extremity. The purpose of this investigation is to provide a comprehensive look at the lower extremity changes experienced during pregnancy and correlate symptoms with underlying etiology in a literature review. In this retrospective study, 100 postpartum women were interviewed regarding the lower extremity changes experienced in pregnancy. The interview included dermatologic, vascular, neurologic, and musculoskeletal portions. Results demonstrate more than 50% of women reported faster toenail growth, roughened toenail texture, increased dryness of the skin, swelling of the foot, ankle, and leg, unsteady gait, increased foot width, and hip pain. Though a majority of patients did not experience the remaining symptoms represented in the interview, all results are pertinent and deserve understanding to provide better insight and care for the pregnant woman. Therefore, a thorough literature review is presented to correlate the outcomes of the present study with previously published research.
                Bookmark

                Author and article information

                Contributors
                Journal
                Int J Womens Dermatol
                Int J Womens Dermatol
                International Journal of Women's Dermatology
                Elsevier
                2352-6475
                21 October 2017
                December 2017
                21 October 2017
                : 3
                : 4
                : 219-224
                Affiliations
                [a ]Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, NY
                [b ]Department of Dermatology, Stanford University School of Medicine, Redwood City, CA
                Author notes
                [* ]Corresponding Author. catherine.motosko@ 123456med.nyu.edu
                Article
                S2352-6475(17)30066-7
                10.1016/j.ijwd.2017.09.003
                5715231
                29234716
                446eddba-eadc-4855-8da9-08d2235181f1
                © 2017 Women's Dermatologic Society. Published by Elsevier Inc.

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                : 26 December 2016
                : 17 September 2017
                : 17 September 2017
                Categories
                Article

                pregnancy,hyperpigmentation,acne,melasma
                pregnancy, hyperpigmentation, acne, melasma

                Comments

                Comment on this article