Blog
About

0
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found

      Age-Dependent Distribution of Acidic Glycosaminoglycans in Human Kidney Tissue

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Acidic glycosaminoglycans (AGAG) of human kidneys prepared from subjects of different ages were purified and determined by an enzymic assay with chondroitinases. The resulting disaccharide units and the undigested AGAG after digesting with the enzymes were identified by paper chromatography, electrophoresis and thin-layer chromatography. The age-dependent changes were: heparan sulfates accounted for 43–74% of total AGAG and the proportion to total AGAG appeared to decrease with advancing age. Dermatan sulfate remained without change. The proportion of hyaluronic acid appeared to decrease at 19–21 years and increased again with aging. The ratio of the 4-type chondroitin sulfate to the 6-type decreased with advancing age.

          Related collections

          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1978
          1978
          02 December 2008
          : 20
          : 2
          : 111-118
          Affiliations
          Department of Medicine and Physical Therapy, University of Tokyo School of Medicine, Tokyo
          Article
          181203 Nephron 1978;20:111–118
          10.1159/000181203
          622208
          © 1978 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 8
          Categories
          Original Paper

          Comments

          Comment on this article