A PANI-Fe ₃O ₄@ZnO nanocomposite: a magnetically separable and applicable catalyst for the synthesis of chromeno-pyrido[ d]pyrimidine derivatives†

Abstract

We report herein green, practical, PANI-Fe ₃O ₄@ZnO-nanocomposite-catalyzed cyclocondensation reactions involving 4-aminocoumarin, 1,3-dimethylbarbituric acid, and aromatic aldehydes in an aqueous medium at room temperature to synthesize 9,11-dimethyl-7-aryl-6 H-chromeno[3′,4′:5,6]pyrido[2,3- d]pyrimidine-6,8,10(9 H,11 H)triones. This research aims to provide an applicable and high-yield protocol that follows the principles of green chemistry, with the use of water as an environmentally benign medium and the PANI-Fe ₃O ₄@ZnO nanocomposite as a magnetically recoverable catalyst.

Abstract

A PANI-Fe ₃O ₄@ZnO nanocomposite is used to prepare a series of novel chromeno-pyrido[ d]pyrimidine derivatives in an aqueous medium at room temperature.