10
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Development of Implants for Prolonged Drug delivery

      , ,

      British Journal of Pharmacy

      University of Huddersfield Press

      Read this article at

      ScienceOpenPublisher
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Despite being apopular and convenient route of drug delivery, the oral route has a number ofdisadvantages. Polymeric sub-dermal implants offer an alternative deliveryroute that may circumvent many of these challenges. In this study, implantswere designed using computer-aided design (CAD) software and fabricated using3D printing. The impact of implant design on the rate of drug release wasinvestigated using methylene blue as a model. It was found that drug releasecould be extended from 2 days to over 40 days as a result of changing implantdesign. Future work will focus on optimisation of implant design with the aimof producing degrading polymeric rate‑controlling membranes to further controldrug release and to conduct further invitro investigation with a drug compound.

          Related collections

          Author and article information

          Journal
          British Journal of Pharmacy
          University of Huddersfield Press
          2058-8356
          April 2 2019
          April 2 2019
          : 4
          : 1
          Article
          10.5920/bjpharm.595
          © 2019

          This work is licensed under a Creative Commons Attribution 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

          Medicine, Pharmacology & Pharmaceutical medicine, Health & Social care

          Comments

          Comment on this article