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Quantitative relationship between end-tidal carbon dioxide and CPR quality during both in-hospital and out-of-hospital cardiac arrest.
Kelsey R Sheak
1 ,
Douglas J Wiebe
2 ,
Marion Leary
1 ,
Saeed Babaeizadeh
3 ,
Trevor C Yuen
4 ,
Dana Zive
5 ,
Pamela C Owens
6 ,
Dana P Edelson
4 ,
Mohamud R Daya
5 ,
Ahamed H Idris
6 ,
Benjamin S Abella
7
Apr 2015
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Abstract
Cardiopulmonary resuscitation (CPR) guidelines recommend the administration of chest compressions (CC) at a standardized rate and depth without guidance from patient physiologic output. The relationship between CC performance and actual CPR-generated blood flow is poorly understood, limiting the ability to define "optimal" CPR delivery. End-tidal carbon dioxide (ETCO2) has been proposed as a surrogate measure of blood flow during CPR, and has been suggested as a tool to guide CPR despite a paucity of clinical data. We sought to quantify the relationship between ETCO2 and CPR characteristics during clinical resuscitation care.