33
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Single Intramuscular-dose Toxicity of Samgihwalryeok-Pharmacopuncture in Sprague-Dawley Rats

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Objectives:

          This study was performed to examine the single-dose toxicity of Samgihwalryeok pharmacopuncture.

          Methods:

          Forty six-week-old Sprague-Dawley (SD) rats were divided into four groups of 10 rats each; each group was then sub-divided into two smaller groups, one of five males and the other of five females. Group 1 (G1, control) received 1.0 mL of normal saline solution, while group 2 (G2, low-dose group), group 3 (G3, mid-does group, and group 4 (G4, high-dose group) received 0.1, 0.5, and 1.0 mL of Samgihwalryeok pharmacopuncture, respectively.

          Results:

          No mortalities or clinical signs were observed in the four groups. Also, no significant changes in body weights were observed among the group, and no significant differences in hematology/biochemistry, necropsy, or histopathology results were noted.

          Conclusion:

          The above findings suggest that treatment with Samgihwalryeok pharmacopuncture is relatively safe. Further studies on this subject are needed.

          Related collections

          Most cited references19

          • Record: found
          • Abstract: not found
          • Article: not found

          [Toxicology]

          (1984)
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            [Researches on parmacopuncture]

            (1995)
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              [Korea Food & Drug Administration notification]

              (2005)
                Bookmark

                Author and article information

                Journal
                J Pharmacopuncture
                J Pharmacopuncture
                J Pharmacopunct
                Journal of Pharmacopuncture
                KOREAN PHARMACOPUNCTURE INSTITUTE
                2093-6966
                2234-6856
                June 2014
                : 17
                : 2
                : 46-56
                Affiliations
                [1 ] Department of Acupuncture & Moxibustion Medicine, Wonkwang Gwangju Oriental Medical Hospital, Gwangju, Korea
                [2 ] Department of Meridians & Acupoints, College of Oriental Medicine, Wonkwang University, Iksan, Korea
                Author notes
                * Corresponding Author Ahn Seong-Hun. Department of Meridians & Acupoints, College of Oriental Medicine, Wonkwang University, 344-2 Shinyong-Dong, Iksan, Korea. Tel: +82-63-850-6983 Fax: +82-63-857-6458 E-mail: drpoint@ 123456wku.ac.kr
                Article
                10.3831/KPI.2014.17.016
                4331996
                454a2f52-b7e2-4d6c-af75-885bda3a3a13
                Copyright ©2014, KOREAN PHARMACOPUNCTURE INSTITUTE

                This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 06 March 2014
                : 19 May 2014
                Categories
                Original Article

                acupuncture,pharmacopuncture,samgihwalryeok pharmacopuncture,single toxicity test

                Comments

                Comment on this article