Identification of a distinct phenotype of elderly latent autoimmune diabetes in adults: LADA China Study 8.

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Abstract

Latent autoimmune diabetes in adults (LADA) exhibits significant clinical heterogeneity, but the underlying causes remain unclear. The aim of this study was to investigate whether age of onset of LADA contributes to the observed clinical heterogeneity by comparing the clinical, metabolic, and immunogenetic characteristics between elderly and young LADA patients.

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Journal

Journal ID (iso-abbrev): Diabetes Metab Res Rev

Title: Diabetes/metabolism research and reviews

Publisher: Wiley

ISSN (Electronic): 1520-7560

ISSN (Print): 1520-7552

Publication date (Electronic): January 2019

Volume: 35

Issue: 1

Affiliations

[1 ] Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

[2 ] Key Laboratory of Diabetes Immunology (Central South University), Ministry of Education, National Clinical Research Center for Metabolic Disease, Changsha, China.

[3 ] Department of Endocrinology, Heji Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi, China.

[4 ] Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.

[5 ] Division of Endocrinology, Metabolism, and Nutrition, Rutgers University-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

[6 ] Department of Diabetes and Metabolic Medicine, Blizard Institute, London, UK.

Article

DOI: 10.1002/dmrr.3068

PubMed ID: 30160000

SO-VID: 45a7b912-152e-4f07-aa40-e9b925419874

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Keywords: class II antigens,LADA,metabolic syndrome,latent autoimmune diabetes in adults,clinical characteristics

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Keywords: class II antigens, LADA, metabolic syndrome, latent autoimmune diabetes in adults, clinical characteristics

Identification of a distinct phenotype of elderly latent autoimmune diabetes in adults: LADA China Study 8.

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