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      Single Cell Protein—State-of-the-Art, Industrial Landscape and Patents 2001–2016

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          Abstract

          By 2050, the world would need to produce 1,250 million tonnes of meat and dairy per year to meet global demand for animal-derived protein at current consumption levels. However, growing demand for protein will not be met sustainably by increasing meat and dairy production because of the low efficiency of converting feed to meat and dairy products. New solutions are needed. Single cell protein (SCP), i.e., protein produced in microbial and algal cells, is an option with potential. Much of the recent interest in SCP has focused on the valorisation of side streams by using microorganisms to improve their protein content, which can then be used in animal feed. There is also increased use of mixed populations, rather than pure strains in the production of SCP. In addition, the use of methane as a carbon source for SCP is reaching commercial scales and more protein-rich products are being derived from algae for both food and feed. The following review addresses the latest developments in SCP production from various organisms, giving an overview of commercial exploitation, a review of recent advances in the patent landscape (2001–2016) and a list of industrial players in the SCP field.

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          Food fermentations: microorganisms with technological beneficial use.

          Microbial food cultures have directly or indirectly come under various regulatory frameworks in the course of the last decades. Several of those regulatory frameworks put emphasis on "the history of use", "traditional food", or "general recognition of safety". Authoritative lists of microorganisms with a documented use in food have therefore come into high demand. One such list was published in 2002 as a result of a joint project between the International Dairy Federation (IDF) and the European Food and Feed Cultures Association (EFFCA). The "2002 IDF inventory" has become a de facto reference for food cultures in practical use. However, as the focus mainly was on commercially available dairy cultures, there was an unmet need for a list with a wider scope. We present an updated inventory of microorganisms used in food fermentations covering a wide range of food matrices (dairy, meat, fish, vegetables, legumes, cereals, beverages, and vinegar). We have also reviewed and updated the taxonomy of the microorganisms used in food fermentations in order to bring the taxonomy in agreement with the current standing in nomenclature. Copyright © 2011 Elsevier B.V. All rights reserved.
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            Bioprocess engineering of microalgae to produce a variety of consumer products

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              Yarrowia lipolytica: safety assessment of an oleaginous yeast with a great industrial potential.

              Yarrowia lipolytica has been developed as a production host for a large variety of biotechnological applications. Efficacy and safety studies have demonstrated the safe use of Yarrowia-derived products containing significant proportions of Yarrowia biomass (as for DuPont's eicosapentaenoic acid-rich oil) or with the yeast itself as the final product (as for British Petroleum's single-cell protein product). The natural occurrence of the species in food, particularly cheese, other dairy products and meat, is a further argument supporting its safety. The species causes rare opportunistic infections in severely immunocompromised or otherwise seriously ill people with other underlying diseases or conditions. The infections can be treated effectively by the use of regular antifungal drugs, and in some cases even disappeared spontaneously. Based on our assessment, we conclude that Y. lipolytica is a "safe-to-use" organism.
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                Author and article information

                Contributors
                Journal
                Front Microbiol
                Front Microbiol
                Front. Microbiol.
                Frontiers in Microbiology
                Frontiers Media S.A.
                1664-302X
                13 October 2017
                2017
                : 8
                : 2009
                Affiliations
                VTT Technical Research Centre of Finland Ltd. , Espoo, Finland
                Author notes

                Edited by: Andrea Gomez-Zavaglia, Center for Research and Development in Food Cryotechnology (CIDCA, CONICET), Argentina

                Reviewed by: Hong-Bo Xin, Nanchang University, China; Klaas J. Jan Hellingwerf, University of Amsterdam, Netherlands

                *Correspondence: Marilyn G. Wiebe marilyn.wiebe@ 123456vtt.fi

                This article was submitted to Food Microbiology, a section of the journal Frontiers in Microbiology

                Article
                10.3389/fmicb.2017.02009
                5645522
                29081772
                45d5bc82-d7c6-409a-98e7-c7dae3954928
                Copyright © 2017 Ritala, Häkkinen, Toivari and Wiebe.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 03 August 2017
                : 29 September 2017
                Page count
                Figures: 0, Tables: 8, Equations: 0, References: 108, Pages: 18, Words: 14604
                Funding
                Funded by: Teknologian Tutkimuskeskus VTT 10.13039/501100007167
                Categories
                Microbiology
                Review

                Microbiology & Virology
                single cell protein,scp,algae,bacteria,fungi,microbial protein,quorn™
                Microbiology & Virology
                single cell protein, scp, algae, bacteria, fungi, microbial protein, quorn™

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