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      About Digestion: 3.2 Impact Factor I 6.4 CiteScore I 0.914 Scimago Journal & Country Rank (SJR)

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      Assessment of the Quality and Content of Clinical Practice Guidelines on Irritable Bowel Syndrome Using the AGREE II Instrument

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          Abstract

          Objectives: The aim of the study was to assess the quality of guidelines on irritable bowel syndrome (IBS) using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument and identify concordance of different commendations. Materials and Methods: A systematic search was undertaken from inception to May 2018. Two reviewers independently selected the titles and abstracts. The guidelines included were assessed using the AGREE II instrument. The consistency of evaluations was calculated using intra-class correlation coefficients with 95% CI. Results: From 994 records, 7 guidelines were included. Most of guidelines got a moderate score of AGREE II. The highest median scores were achieved for scope and purpose and clarity and presentation (69.4%), while the lowest median scores across guidelines were for applicability (50.0%). Most of the nonpharmacologic management recommendations for IBS were similar. However, there also existed some differences on pharmacologic between different guidelines. Conclusions: The guidelines on IBS varied in quality and there were discrepancies about recommendations and recommendation grades. There is some space to improvement the quality of methodological rigor in development and reporting within clinical guidelines.

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          Author and article information

          Journal
          DIG
          Digestion
          10.1159/issn.0012-2823
          Digestion
          S. Karger AG
          0012-2823
          1421-9867
          2020
          July 2020
          10 April 2019
          : 101
          : 4
          : 355-365
          Affiliations
          [_a] aSchool of Public Health, Evidence-Based Social Science Research Center, Lanzhou University, Lanzhou, China
          [_b] bEvidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China
          [_c] cKey Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, Lanzhou, China
          [_d] dChinese GRADE Centre, Lanzhou University, Lanzhou, China
          [_e] eGansu Chinese Medicine University, Lanzhou, China
          [_f] fChinese Medicine Faculty of Hong Kong Baptist University, Hong Kong, China
          [_g] gInstitute of Clinical Research and Evidence Based Medicine, Gansu Provincial Hospital, Lanzhou, China
          [_h] hThe Center of Endoscopic Surgery of 451 Hospital of PLA, Xian, China
          Author notes
          *Kehu Yang, Evidence-Based Medicine Center, School of Basic Medical Sciences; Evidence-Based Social Sciences Research Center, Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, 199 Donggang West Road, Lanzhou University, Lanzhou 730000 (PR China), E-Mail kehuyangebm2006@126.com, , Xinmin Yang, The Center of Endoscopic Surgery of 451 Hospital of PLA, Xian 710054 (PR China), E-Mail yanxm200816@163.com
          Author information
          https://orcid.org/0000-0002-5542-9950
          Article
          499838 Digestion 2020;101:355–365
          10.1159/000499838
          30970372
          461efece-193c-4b35-b902-f450c4391871
          © 2019 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 08 January 2019
          : 21 March 2019
          Page count
          Figures: 1, Tables: 6, Pages: 11
          Categories
          Research Article

          Oncology & Radiotherapy,Gastroenterology & Hepatology,Surgery,Nutrition & Dietetics,Internal medicine
          AGREE II,Guidelines,Irritable bowel syndrome

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