Ventricular Repolarization during Smoking

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Abstract

30 healthy individuals and 20 patients suffering from coronary artery disease had orthogonal electrocardiograms taken at rest, after moderate exercise and during smoking. The heart rate increased during smoking to approximately the same level as after exercise. The unadjusted Q-T interval did not change significantly during smoking, but it significantly decreased after exercise when its value was compared with that at rest. The linearly corrected Q-T (Q-T/R-R) increased significantly after exercise and even more during smoking. The parabolically corrected Q-T (QTc) increased significantly only during smoking, suggesting that this was not a heart rate dependent phenomenon. The factors responsible for the prolongation of the corrected Q-Ts during smoking could include increased sympathetic tone, slight myocardial ischemia, slight heart decompensation, substances interfering with metabolic processes in the myocardial cell and myocardial strain due to increased cardiac work.

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Author and article information

Journal

Journal ID (publisher-id): CRD

Journal ID (nlm-ta): Cardiology

Journal ID (doi): 10.1159/issn.0008-6312

Title: Cardiology

Publisher: S. Karger AG

ISSN (Print): 0008-6312

ISSN (Electronic): 1421-9751

Publication date Subscription-year: 1973

Publication date (Print): 1973

Publication date (Electronic): 29 October 2008

Volume: 58

Issue: 3

Pages: 139-149

Affiliations

Department of Cardiology, University of Athens Medical School, Hippocration Hospital, Athens

Article

Publisher ID: 169628 Other ID: Cardiology 1973;58:139–149

DOI: 10.1159/000169628

PubMed ID: 4773534

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