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      Ventricular Repolarization during Smoking

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          Abstract

          30 healthy individuals and 20 patients suffering from coronary artery disease had orthogonal electrocardiograms taken at rest, after moderate exercise and during smoking. The heart rate increased during smoking to approximately the same level as after exercise. The unadjusted Q-T interval did not change significantly during smoking, but it significantly decreased after exercise when its value was compared with that at rest. The linearly corrected Q-T (Q-T/R-R) increased significantly after exercise and even more during smoking. The parabolically corrected Q-T (QTc) increased significantly only during smoking, suggesting that this was not a heart rate dependent phenomenon. The factors responsible for the prolongation of the corrected Q-Ts during smoking could include increased sympathetic tone, slight myocardial ischemia, slight heart decompensation, substances interfering with metabolic processes in the myocardial cell and myocardial strain due to increased cardiac work.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1973
          1973
          29 October 2008
          : 58
          : 3
          : 139-149
          Affiliations
          Department of Cardiology, University of Athens Medical School, Hippocration Hospital, Athens
          Article
          169628 Cardiology 1973;58:139–149
          10.1159/000169628
          4773534
          © 1973 S. Karger AG, Basel

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          Page count
          Pages: 11
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