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      Angiotensin-(1-7): pharmacology and new perspectives in cardiovascular treatments.

      Cardiovascular drug reviews
      Angiotensin I, pharmacology, physiology, therapeutic use, Animals, Antihypertensive Agents, Brain, drug effects, Cardiovascular Diseases, drug therapy, Heart, Humans, Kidney, Peptide Fragments, Renin-Angiotensin System

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          Abstract

          Many advances have been made in the cardiovascular field in the last several decades. Among them is the progress completed to date on the heptapeptide member of the renin-angiotensin system (RAS), angiotensin-(1-7) [Ang-(1-7)]. The peptide's beneficial actions against pathophysiological processes, such as cardiac arrhythmia, heart failure, hypertension, renal disease, preeclampsia, and even cancer are continuously being uncovered. This review encompasses the pharmacology of Ang-(1-7) and expounds upon the peptide's potential as a therapeutic agent against pathological processes both within and outside the cardiovascular continuum.

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