114
views
0
recommends
+1 Recommend
3 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Rising rural body-mass index is the main driver of the global obesity epidemic in adults

      research-article
      NCD Risk Factor Collaboration (NCD-RisC)
      majid.ezzati@imperial.ac.uk
      1
      Nature
      Nature Publishing Group UK
      Risk factors, Epidemiology

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1, 2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 36 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017—and more than 80% in some low- and middle-income regions—was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing—and in some countries reversal—of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.

          Abstract

          Contrary to the view that urbanization is a major driver of the global rise in obesity, the global increase in body-mass index is shown to be mostly due to increases in the body-mass indexes of rural populations.

          Related collections

          Most cited references49

          • Record: found
          • Abstract: found
          • Article: found
          Is Open Access

          Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults

          Summary Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. Methods We pooled 2416 population-based studies with measurements of height and weight on 128·9 million participants aged 5 years and older, including 31·5 million aged 5–19 years. We used a Bayesian hierarchical model to estimate trends from 1975 to 2016 in 200 countries for mean BMI and for prevalence of BMI in the following categories for children and adolescents aged 5–19 years: more than 2 SD below the median of the WHO growth reference for children and adolescents (referred to as moderate and severe underweight hereafter), 2 SD to more than 1 SD below the median (mild underweight), 1 SD below the median to 1 SD above the median (healthy weight), more than 1 SD to 2 SD above the median (overweight but not obese), and more than 2 SD above the median (obesity). Findings Regional change in age-standardised mean BMI in girls from 1975 to 2016 ranged from virtually no change (−0·01 kg/m2 per decade; 95% credible interval −0·42 to 0·39, posterior probability [PP] of the observed decrease being a true decrease=0·5098) in eastern Europe to an increase of 1·00 kg/m2 per decade (0·69–1·35, PP>0·9999) in central Latin America and an increase of 0·95 kg/m2 per decade (0·64–1·25, PP>0·9999) in Polynesia and Micronesia. The range for boys was from a non-significant increase of 0·09 kg/m2 per decade (−0·33 to 0·49, PP=0·6926) in eastern Europe to an increase of 0·77 kg/m2 per decade (0·50–1·06, PP>0·9999) in Polynesia and Micronesia. Trends in mean BMI have recently flattened in northwestern Europe and the high-income English-speaking and Asia-Pacific regions for both sexes, southwestern Europe for boys, and central and Andean Latin America for girls. By contrast, the rise in BMI has accelerated in east and south Asia for both sexes, and southeast Asia for boys. Global age-standardised prevalence of obesity increased from 0·7% (0·4–1·2) in 1975 to 5·6% (4·8–6·5) in 2016 in girls, and from 0·9% (0·5–1·3) in 1975 to 7·8% (6·7–9·1) in 2016 in boys; the prevalence of moderate and severe underweight decreased from 9·2% (6·0–12·9) in 1975 to 8·4% (6·8–10·1) in 2016 in girls and from 14·8% (10·4–19·5) in 1975 to 12·4% (10·3–14·5) in 2016 in boys. Prevalence of moderate and severe underweight was highest in India, at 22·7% (16·7–29·6) among girls and 30·7% (23·5–38·0) among boys. Prevalence of obesity was more than 30% in girls in Nauru, the Cook Islands, and Palau; and boys in the Cook Islands, Nauru, Palau, Niue, and American Samoa in 2016. Prevalence of obesity was about 20% or more in several countries in Polynesia and Micronesia, the Middle East and north Africa, the Caribbean, and the USA. In 2016, 75 (44–117) million girls and 117 (70–178) million boys worldwide were moderately or severely underweight. In the same year, 50 (24–89) million girls and 74 (39–125) million boys worldwide were obese. Interpretation The rising trends in children's and adolescents' BMI have plateaued in many high-income countries, albeit at high levels, but have accelerated in parts of Asia, with trends no longer correlated with those of adults. Funding Wellcome Trust, AstraZeneca Young Health Programme.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: found
            Is Open Access

            Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants

            Summary Background One of the global targets for non-communicable diseases is to halt, by 2025, the rise in the age-standardised adult prevalence of diabetes at its 2010 levels. We aimed to estimate worldwide trends in diabetes, how likely it is for countries to achieve the global target, and how changes in prevalence, together with population growth and ageing, are affecting the number of adults with diabetes. Methods We pooled data from population-based studies that had collected data on diabetes through measurement of its biomarkers. We used a Bayesian hierarchical model to estimate trends in diabetes prevalence—defined as fasting plasma glucose of 7·0 mmol/L or higher, or history of diagnosis with diabetes, or use of insulin or oral hypoglycaemic drugs—in 200 countries and territories in 21 regions, by sex and from 1980 to 2014. We also calculated the posterior probability of meeting the global diabetes target if post-2000 trends continue. Findings We used data from 751 studies including 4 372 000 adults from 146 of the 200 countries we make estimates for. Global age-standardised diabetes prevalence increased from 4·3% (95% credible interval 2·4–7·0) in 1980 to 9·0% (7·2–11·1) in 2014 in men, and from 5·0% (2·9–7·9) to 7·9% (6·4–9·7) in women. The number of adults with diabetes in the world increased from 108 million in 1980 to 422 million in 2014 (28·5% due to the rise in prevalence, 39·7% due to population growth and ageing, and 31·8% due to interaction of these two factors). Age-standardised adult diabetes prevalence in 2014 was lowest in northwestern Europe, and highest in Polynesia and Micronesia, at nearly 25%, followed by Melanesia and the Middle East and north Africa. Between 1980 and 2014 there was little change in age-standardised diabetes prevalence in adult women in continental western Europe, although crude prevalence rose because of ageing of the population. By contrast, age-standardised adult prevalence rose by 15 percentage points in men and women in Polynesia and Micronesia. In 2014, American Samoa had the highest national prevalence of diabetes (>30% in both sexes), with age-standardised adult prevalence also higher than 25% in some other islands in Polynesia and Micronesia. If post-2000 trends continue, the probability of meeting the global target of halting the rise in the prevalence of diabetes by 2025 at the 2010 level worldwide is lower than 1% for men and is 1% for women. Only nine countries for men and 29 countries for women, mostly in western Europe, have a 50% or higher probability of meeting the global target. Interpretation Since 1980, age-standardised diabetes prevalence in adults has increased, or at best remained unchanged, in every country. Together with population growth and ageing, this rise has led to a near quadrupling of the number of adults with diabetes worldwide. The burden of diabetes, both in terms of prevalence and number of adults affected, has increased faster in low-income and middle-income countries than in high-income countries. Funding Wellcome Trust.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Global nutrition transition and the pandemic of obesity in developing countries.

              Decades ago, discussion of an impending global pandemic of obesity was thought of as heresy. But in the 1970s, diets began to shift towards increased reliance upon processed foods, increased away-from-home food intake, and increased use of edible oils and sugar-sweetened beverages. Reductions in physical activity and increases in sedentary behavior began to be seen as well. The negative effects of these changes began to be recognized in the early 1990s, primarily in low- and middle-income populations, but they did not become clearly acknowledged until diabetes, hypertension, and obesity began to dominate the globe. Now, rapid increases in the rates of obesity and overweight are widely documented, from urban and rural areas in the poorest countries of sub-Saharan Africa and South Asia to populations in countries with higher income levels. Concurrent rapid shifts in diet and activity are well documented as well. An array of large-scale programmatic and policy measures are being explored in a few countries; however, few countries are engaged in serious efforts to prevent the serious dietary challenges being faced. © 2012 International Life Sciences Institute.
                Bookmark

                Author and article information

                Journal
                Nature
                Nature
                Nature
                Nature Publishing Group UK (London )
                0028-0836
                1476-4687
                8 May 2019
                8 May 2019
                2019
                : 569
                : 7755
                : 260-264
                Affiliations
                [1 ]ISNI 0000 0001 2113 8111, GRID grid.7445.2, Imperial College London, ; London, UK
                [2 ]ISNI 0000 0001 2232 2818, GRID grid.9759.2, University of Kent, ; Canterbury, UK
                [3 ]ISNI 0000 0001 0710 330X, GRID grid.15822.3c, Middlesex University, ; London, UK
                [4 ]ISNI 0000 0001 2181 7878, GRID grid.47840.3f, University of California Berkeley, ; Berkeley, CA USA
                [5 ]ISNI 0000000121633745, GRID grid.3575.4, World Health Organization, ; Geneva, Switzerland
                [6 ]ISNI 0000 0004 0470 5905, GRID grid.31501.36, Seoul National University, ; Seoul, South Korea
                [7 ]ISNI 0000 0001 0657 4636, GRID grid.4808.4, University of Zagreb, ; Zagreb, Croatia
                [8 ]ISNI 0000 0001 2163 0069, GRID grid.416738.f, US Centers for Disease Control and Prevention, ; Atlanta, GA USA
                [9 ]ISNI 0000 0001 0673 9488, GRID grid.11100.31, Universidad Peruana Cayetano Heredia, ; Lima, Peru
                [10 ]ISNI 0000 0001 0633 6224, GRID grid.7147.5, Aga Khan University, ; Karachi, Pakistan
                [11 ]ISNI 0000 0004 0473 9646, GRID grid.42327.30, The Hospital for Sick Children, ; Toronto, Ontario Canada
                [12 ]ISNI 000000041936754X, GRID grid.38142.3c, Harvard T. H. Chan School of Public Health, ; Boston, MA USA
                [13 ]GRID grid.450284.f, Ministry of Health, ; Victoria, Seychelles
                [14 ]ISNI 0000 0001 2165 4204, GRID grid.9851.5, University of Lausanne, ; Lausanne, Switzerland
                [15 ]ISNI 0000 0001 0504 4027, GRID grid.22248.3e, Victor Babeş University of Medicine and Pharmacy Timisoara, ; Timisoara, Romania
                [16 ]GRID grid.412886.1, The University of the West Indies, ; Cave Hill, Barbados
                [17 ]ISNI 0000 0004 1936 834X, GRID grid.1013.3, University of Sydney, ; Sydney, New South Wales Australia
                [18 ]GRID grid.482562.f, National Institutes of Biomedical Innovation, Health and Nutrition, ; Tokyo, Japan
                [19 ]ISNI 0000 0000 9155 0024, GRID grid.415021.3, South African Medical Research Council, ; Cape Town, South Africa
                [20 ]ISNI 0000 0004 0496 9898, GRID grid.419610.b, ICMR-National Institute of Nutrition, ; Hyderabad, India
                [21 ]ISNI 0000 0004 1936 9094, GRID grid.40263.33, Brown University, ; Providence, RI USA
                [22 ]ISNI 0000 0004 0621 1570, GRID grid.7269.a, Ain Shams University, ; Cairo, Egypt
                [23 ]ISNI 0000 0004 1937 0626, GRID grid.4714.6, Karolinska Institutet, ; Stockholm, Sweden
                [24 ]ISNI 0000 0001 0721 6013, GRID grid.8954.0, University of Ljubljana, ; Ljubljana, Slovenia
                [25 ]ISNI 0000 0001 0690 5255, GRID grid.415759.b, Ministry of Health Malaysia, ; Kuala Lumpur, Malaysia
                [26 ]ISNI 0000 0001 2112 4705, GRID grid.466544.1, Caja Costarricense de Seguro Social, ; San José, Costa Rica
                [27 ]ISNI 0000 0001 2298 706X, GRID grid.16662.35, Al-Quds University, ; East Jerusalem, Palestine
                [28 ]National Center of Public Healthcare, Nur-Sultan, Kazakhstan
                [29 ]Center for Diabetes and Endocrine Care, Srinagar, India
                [30 ]GRID grid.412774.3, Usmanu Danfodiyo University Teaching Hospital, ; Sokoto, Nigeria
                [31 ]ISNI 0000 0004 0575 2412, GRID grid.22532.34, Birzeit University, ; Birzeit, Palestine
                [32 ]ISNI 0000 0001 1091 9430, GRID grid.419157.f, Instituto Mexicano del Seguro Social, ; Mexico City, Mexico
                [33 ]ISNI 0000 0004 0367 2697, GRID grid.1014.4, Flinders University, ; Adelaide, South Australia Australia
                [34 ]ISNI 0000 0004 1937 0490, GRID grid.10223.32, Mahidol University, ; Nakhon Pathom, Thailand
                [35 ]ISNI 0000 0001 0746 8691, GRID grid.52681.38, BRAC University, ; Dhaka, Bangladesh
                [36 ]GRID grid.484092.3, Food and Nutrition Research Institute, ; Taguig, The Philippines
                [37 ]ISNI 0000 0001 0698 4037, GRID grid.416850.e, Instituto Nacional de Ciencias Médicas y Nutrición, ; Mexico City, Mexico
                [38 ]ISNI 0000000084992262, GRID grid.7177.6, University of Amsterdam, ; Amsterdam, The Netherlands
                [39 ]ISNI 0000 0001 0166 0922, GRID grid.411705.6, Tehran University of Medical Sciences, ; Tehran, Iran
                [40 ]Non-Communicable Diseases Research Center, Tehran, Iran
                [41 ]ISNI 0000 0001 2297 4381, GRID grid.7704.4, University of Bremen, ; Bremen, Germany
                [42 ]The National Center for Diabetes, Endocrinology and Genetics, Amman, Jordan
                [43 ]Aldara Hospital and Medical Center, Riyadh, Saudi Arabia
                [44 ]ISNI 0000 0004 0580 0891, GRID grid.452607.2, King Abdullah International Medical Research Center, ; Riyadh, Saudi Arabia
                [45 ]ISNI 0000 0004 1773 5396, GRID grid.56302.32, King Saud University, ; Riyadh, Saudi Arabia
                [46 ]ISNI 0000 0001 0417 0814, GRID grid.265727.3, Universiti Malaysia Sabah, ; Kota Kinabalu, Malaysia
                [47 ]ISNI 0000 0004 0621 531X, GRID grid.451012.3, Luxembourg Institute of Health, ; Strassen, Luxembourg
                [48 ]ISNI 0000 0004 0637 3393, GRID grid.453496.9, Kuwait Institute for Scientific Research, ; Safat, Kuwait
                [49 ]ISNI 0000 0001 0619 1117, GRID grid.412125.1, King Abdulaziz University, ; Jeddah, Saudi Arabia
                [50 ]ISNI 0000 0004 0592 275X, GRID grid.417617.2, ISGlobal Centre for Research in Environmental Epidemiology, ; Barcelona, Spain
                [51 ]ISNI 0000 0001 1942 4602, GRID grid.483405.e, World Health Organization Regional Office for the Eastern Mediterranean, ; Cairo, Egypt
                [52 ]ISNI 0000 0004 1766 7856, GRID grid.414537.0, Bombay Hospital and Medical Research Centre, ; Mumbai, India
                [53 ]ISNI 0000 0001 2242 6780, GRID grid.503422.2, University of Lille, ; Lille, France
                [54 ]ISNI 0000 0004 0471 8845, GRID grid.410463.4, Lille University Hospital, ; Lille, France
                [55 ]ISNI 0000 0004 0425 469X, GRID grid.8991.9, London School of Hygiene & Tropical Medicine, ; London, UK
                [56 ]GRID grid.477239.c, Western Norway University of Applied Sciences, ; Sogndal, Norway
                [57 ]ISNI 0000 0000 8567 2092, GRID grid.412285.8, Norwegian School of Sport Sciences, ; Oslo, Norway
                [58 ]ISNI 0000 0001 0674 042X, GRID grid.5254.6, University of Copenhagen, ; Copenhagen, Denmark
                [59 ]ISNI 0000 0004 1794 3718, GRID grid.429336.9, Madras Diabetes Research Foundation, ; Chennai, India
                [60 ]ISNI 0000 0004 0612 8339, GRID grid.488433.0, Zahedan University of Medical Sciences, ; Zahedan, Iran
                [61 ]National Institute of Public Health, Tunis, Tunisia
                [62 ]ISNI 0000 0001 1503 7226, GRID grid.5808.5, Institute of Public Health of the University of Porto, ; Porto, Portugal
                [63 ]ISNI 0000 0001 1541 4204, GRID grid.418193.6, Norwegian Institute of Public Health, ; Oslo, Norway
                [64 ]University of Massachusetts, Amherst, MA USA
                [65 ]Abt Associates, Kathmandu, Nepal
                [66 ]ISNI 0000 0004 0640 0021, GRID grid.14013.37, University of Iceland, ; Reykjavik, Iceland
                [67 ]ISNI 0000 0001 2173 8504, GRID grid.412661.6, University of Yaoundé 1, ; Yaoundé, Cameroon
                [68 ]ISNI 0000 0001 2134 6519, GRID grid.411221.5, Federal University of Pelotas, ; Pelotas, Brazil
                [69 ]ISNI 0000 0004 0593 4427, GRID grid.430766.0, University of Medicine 1, ; Yangon, Myanmar
                [70 ]ISNI 0000 0001 0941 4873, GRID grid.10858.34, University of Oulu, ; Oulu, Finland
                [71 ]Regional Authority of Public Health, Banska Bystrica, Slovakia
                [72 ]ISNI 0000 0001 1503 7226, GRID grid.5808.5, University of Porto Medical School, ; Porto, Portugal
                [73 ]GRID grid.411600.2, Shahid Beheshti University of Medical Sciences, ; Tehran, Iran
                [74 ]ISNI 0000 0004 1767 225X, GRID grid.19096.37, Indian Council of Medical Research, ; New Delhi, India
                [75 ]ISNI 0000 0000 9350 8874, GRID grid.411702.1, Bispebjerg and Frederiksberg Hospital, ; Copenhagen, Denmark
                [76 ]GRID grid.444917.b, University of Science and Technology, ; Sana’a, Yemen
                [77 ]ISNI 0000 0001 2165 3025, GRID grid.8267.b, Medical University of Lodz, ; Lodz, Poland
                [78 ]ISNI 0000 0001 0531 3426, GRID grid.11451.30, Medical University of Gdansk, ; Gdansk, Poland
                [79 ]ISNI 0000000119578126, GRID grid.5515.4, Universidad Autónoma de Madrid, ; Madrid, Spain
                [80 ]ISNI 0000 0004 1762 5517, GRID grid.10776.37, University of Palermo, ; Palermo, Italy
                [81 ]ISNI 0000 0001 0505 4321, GRID grid.4437.4, Pan American Health Organization, ; Washington, DC USA
                [82 ]ISNI 0000 0001 2168 4024, GRID grid.31143.34, Mohammed V University de Rabat, ; Rabat, Morocco
                [83 ]ISNI 0000 0001 0670 7996, GRID grid.411227.3, University of Pernambuco, ; Recife, Brazil
                [84 ]ISNI 0000 0004 1936 8200, GRID grid.55602.34, Dalhousie University, ; Halifax, Nova Scotia Canada
                [85 ]ISNI 0000 0001 0097 5797, GRID grid.37553.37, Jordan University of Science and Technology, ; Irbid, Jordan
                [86 ]ISNI 0000 0001 2165 7632, GRID grid.411204.2, Federal University of Maranhao, ; Sao Luis, Brazil
                [87 ]ISNI 0000 0004 0387 8740, GRID grid.443453.1, Kazakh National Medical University, ; Almaty, Kazakhstan
                [88 ]ISNI 0000 0004 0372 3343, GRID grid.9654.e, University of Auckland, ; Auckland, New Zealand
                [89 ]ISNI 0000 0001 0768 2743, GRID grid.7886.1, University College Dublin, ; Dublin, Ireland
                [90 ]ISNI 0000000122959819, GRID grid.12574.35, University Tunis El Manar, ; Tunis, Tunisia
                [91 ]ISNI 0000 0004 0444 280X, GRID grid.493908.f, Federal Ministry of Labour, Social Affairs, Health and Consumer Protection, ; Vienna, Austria
                [92 ]Cafam University Foundation, Bogota, Colombia
                [93 ]ISNI 0000 0004 0432 6841, GRID grid.45083.3a, Lithuanian University of Health Sciences, ; Kaunas, Lithuania
                [94 ]ISNI 0000 0004 1937 0722, GRID grid.11899.38, University of São Paulo, ; São Paulo, Brazil
                [95 ]ISNI 0000 0004 1767 9806, GRID grid.414133.0, B. J. Medical College, ; Ahmedabad, India
                [96 ]Chirayu Medical College, New Delhi, India
                [97 ]ISNI 0000 0004 1767 9128, GRID grid.451715.3, Sunder Lal Jain Hospital, ; Delhi, India
                [98 ]ISNI 0000 0000 9459 9325, GRID grid.464402.0, Shandong University of Traditional Chinese Medicine, ; Shandong, China
                [99 ]ISNI 0000 0004 0368 8293, GRID grid.16821.3c, Shanghai Jiao-Tong University School of Medicine, ; Shanghai, China
                [100 ]Institute of Medical Research and Medicinal Plant Studies, Yaoundé, Cameroon
                [101 ]ISNI 0000 0004 0389 9736, GRID grid.482657.a, Ufa Eye Research Institute, ; Ufa, Russia
                [102 ]ISNI 0000 0000 8639 0425, GRID grid.452693.f, Nepal Health Research Council, ; Kathmandu, Nepal
                [103 ]ISNI 0000 0001 2182 0188, GRID grid.12316.37, University of Montenegro, ; Niksic, Montenegro
                [104 ]GRID grid.449721.d, University of Greenland, ; Nuuk, Greenland
                [105 ]ISNI 0000 0001 0728 0170, GRID grid.10825.3e, University of Southern Denmark, ; Odense, Denmark
                [106 ]ISNI 0000 0004 1936 8921, GRID grid.5510.1, University of Oslo, ; Oslo, Norway
                [107 ]ISNI 0000 0000 9919 9582, GRID grid.8761.8, University of Gothenburg, ; Gothenburg, Sweden
                [108 ]ISNI 0000 0001 2208 0118, GRID grid.31147.30, National Institute for Public Health and the Environment, ; Bilthoven, The Netherlands
                [109 ]ISNI 0000 0001 2336 6580, GRID grid.7605.4, University of Turin, ; Turin, Italy
                [110 ]ISNI 0000000121901201, GRID grid.83440.3b, University College London, ; London, UK
                [111 ]ISNI 0000 0004 0368 0654, GRID grid.4425.7, Liverpool John Moores University, ; Liverpool, UK
                [112 ]ISNI 0000 0001 2224 0361, GRID grid.59025.3b, Nanyang Technological University, ; Singapore, Singapore
                [113 ]ISNI 0000 0004 0390 0098, GRID grid.418213.d, German Institute of Human Nutrition, ; Potsdam, Germany
                [114 ]ISNI 0000000121657640, GRID grid.11630.35, Universidad de la República, ; Montevideo, Uruguay
                [115 ]ISNI 0000 0004 0637 5938, GRID grid.418248.3, CEMIC, ; Buenos Aires, Argentina
                [116 ]ISNI 0000 0004 1760 3561, GRID grid.419543.e, IRCCS Neuromed, ; Pozzilli, Italy
                [117 ]ISNI 0000 0001 2353 1689, GRID grid.11417.32, Toulouse University School of Medicine, ; Toulouse, France
                [118 ]ISNI 0000 0004 1937 0650, GRID grid.7400.3, University of Zurich, ; Zurich, Switzerland
                [119 ]GRID grid.412972.b, University Hospital of Varese, ; Varese, Italy
                [120 ]ISNI 0000 0004 0626 3338, GRID grid.410569.f, University Hospital KU Leuven, ; Leuven, Belgium
                [121 ]ISNI 0000 0004 0608 6394, GRID grid.491198.c, Flemish Agency for Care and Health, ; Brussels, Belgium
                [122 ]ISNI 0000 0001 2069 7798, GRID grid.5342.0, Ghent University, ; Ghent, Belgium
                [123 ]ISNI 0000 0004 0637 349X, GRID grid.434547.5, FrieslandCampina, ; Amersfoort, The Netherlands
                [124 ]ISNI 0000 0001 2155 0982, GRID grid.8171.f, Universidad Central de Venezuela, ; Caracas, Venezuela
                [125 ]ISNI 0000 0001 0944 9128, GRID grid.7491.b, Bielefeld University, ; Bielefeld, Germany
                [126 ]ISNI 0000 0004 0639 2949, GRID grid.420226.0, World Health Organization Regional Office for Europe, ; Copenhagen, Denmark
                [127 ]ISNI 0000 0004 0492 0584, GRID grid.7497.d, German Cancer Research Center, ; Heidelberg, Germany
                [128 ]ISNI 0000 0004 0463 8394, GRID grid.419977.5, The Fred Hollows Foundation, ; Auckland, New Zealand
                [129 ]ISNI 0000 0000 9828 7548, GRID grid.8194.4, University of Medicine and Pharmacy Bucharest, ; Bucharest, Romania
                [130 ]University College Copenhagen, Copenhagen, Denmark
                [131 ]ISNI 0000 0004 4688 1528, GRID grid.414773.2, Institute of Public Health, ; Tirana, Albania
                [132 ]ISNI 0000 0001 0693 825X, GRID grid.47244.31, Cork Institute of Technology, ; Cork, Ireland
                [133 ]ISNI 0000000121060879, GRID grid.10041.34, Universidad de La Laguna, ; Tenerife, Spain
                [134 ]ISNI 0000 0001 2176 9482, GRID grid.4462.4, University of Malta, ; Pietà, Malta
                [135 ]ISNI 0000 0001 2264 7217, GRID grid.152326.1, Vanderbilt University, ; Nashville, TN USA
                [136 ]Ministry of Health, Tongatapu, Tonga
                [137 ]ISNI 0000 0001 2164 2780, GRID grid.418590.1, Canadian Fitness and Lifestyle Research Institute, ; Ottawa, Ontario Canada
                [138 ]ISNI 0000 0001 2295 9747, GRID grid.411265.5, Hospital Santa Maria, ; Lisbon, Portugal
                [139 ]ISNI 0000 0001 2186 0630, GRID grid.31564.35, Karadeniz Technical University, ; Trabzon, Turkey
                [140 ]ISNI 0000 0001 2166 6619, GRID grid.9601.e, Istanbul University, ; Istanbul, Turkey
                [141 ]ISNI 0000 0001 2170 9332, GRID grid.411198.4, Universidade Federal de Juiz de Fora, ; Juiz de Fora, Brazil
                [142 ]Ministry of Public Health, Asunción, Paraguay
                [143 ]Cardiologia di Mercato S. Severino Hospital, Mercato San Severino, Italy
                [144 ]ISNI 0000 0004 1937 0626, GRID grid.4714.6, Karolinska Institutet, ; Huddinge, Sweden
                [145 ]Centro de Estudios sobre Nutrición Infantil, Buenos Aires, Argentina
                [146 ]ISNI 0000 0001 1503 7226, GRID grid.5808.5, University of Porto, ; Porto, Portugal
                [147 ]ISNI 0000000109410645, GRID grid.11794.3a, Santiago de Compostela University, ; Santiago de Compostela, Spain
                [148 ]Associazione Calabrese di Epatologia, Reggio Calabria, Italy
                [149 ]GRID grid.415700.7, Ministry of Health, ; Ankara, Turkey
                [150 ]ISNI 0000 0004 1937 0300, GRID grid.420153.1, Food and Agriculture Organization of the United Nations, ; Rome, Italy
                [151 ]ISNI 0000 0001 2200 7498, GRID grid.8532.c, Federal University of Rio Grande, ; Rio Grande, Brazil
                [152 ]ISNI 0000 0004 5899 1679, GRID grid.479916.4, India Diabetes Research Foundation, ; Chennai, India
                [153 ]ISNI 0000 0004 0385 0924, GRID grid.428397.3, Duke-NUS Medical School, ; Singapore, Singapore
                [154 ]ISNI 0000 0000 9698 7401, GRID grid.496666.d, National Institute of Medical Statistics, ; New Delhi, India
                [155 ]ISNI 0000 0001 2287 1366, GRID grid.28665.3f, Academia Sinica, ; Taipei, Taiwan
                [156 ]ISNI 0000 0004 1771 7032, GRID grid.418633.b, Capital Institute of Pediatrics, ; Beijing, China
                [157 ]ISNI 0000 0004 1936 7961, GRID grid.26009.3d, Duke University, ; Durham, NC USA
                [158 ]ISNI 0000 0004 1757 7033, GRID grid.459652.9, Kailuan General Hospital, ; Tangshan, China
                [159 ]ISNI 0000 0004 1936 8948, GRID grid.4991.5, University of Oxford, ; Oxford, UK
                [160 ]ISNI 0000 0001 2107 2845, GRID grid.413795.d, The Gertner Institute for Epidemiology and Health Policy Research, ; Ramat Gan, Israel
                [161 ]National Centre of Public Health and Analyses, Sofia, Bulgaria
                [162 ]ISNI 0000 0001 0726 5157, GRID grid.5734.5, University of Bern, ; Lausanne, Switzerland
                [163 ]GRID grid.454740.6, Ministry of Health and Welfare, ; Taipei, Taiwan
                [164 ]Murcia Health Council, Murcia, Spain
                [165 ]ISNI 0000 0004 0470 5905, GRID grid.31501.36, Seoul National University College of Medicine, ; Seoul, South Korea
                [166 ]ISNI 0000 0004 1763 8617, GRID grid.418967.5, Korea Centers for Disease Control and Prevention, ; Cheongju-si, South Korea
                [167 ]ISNI 0000 0001 2188 478X, GRID grid.410543.7, Universidade Estadual Paulista, ; Presidente Prudente, Brazil
                [168 ]ISNI 0000 0001 2198 0923, GRID grid.411728.9, Medical University of Silesia, ; Katowice, Poland
                [169 ]ISNI 0000 0004 1937 116X, GRID grid.4491.8, Charles University in Prague, ; Prague, Czech Republic
                [170 ]ISNI 0000 0004 0608 6888, GRID grid.448223.b, Thomayer Hospital, ; Prague, Czech Republic
                [171 ]Primary Health Care, Floriana, Malta
                [172 ]ISNI 0000 0000 9828 7548, GRID grid.8194.4, Carol Davila University of Medicine and Pharmacy, ; Bucharest, Romania
                [173 ]ISNI 0000 0001 0668 7884, GRID grid.5596.f, Katholieke Universiteit Leuven, ; Leuven, Belgium
                [174 ]ISNI 0000 0001 2182 2255, GRID grid.28046.38, Statistics Canada, Ottawa, ; Ontario, Canada
                [175 ]Agency for Preventive and Social Medicine, Bregenz, Austria
                [176 ]ISNI 0000 0001 2188 7235, GRID grid.411237.2, Universidade Federal de Santa Catarina, ; Florianópolis, Brazil
                [177 ]ISNI 0000 0004 1936 9297, GRID grid.5491.9, University of Southampton, ; Southampton, UK
                [178 ]ISNI 0000 0001 2159 9858, GRID grid.8970.6, Institut Pasteur de Lille, ; Lille, France
                [179 ]Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi
                [180 ]ISNI 0000 0004 5930 4615, GRID grid.484042.e, CIBEROBN, ; Madrid, Spain
                [181 ]National Institute of Public Health, Bucharest, Romania
                [182 ]GRID grid.8295.6, Eduardo Mondlane University, ; Maputo, Mozambique
                [183 ]ISNI 0000 0001 1940 4177, GRID grid.5326.2, National Council of Research, ; Reggio Calabria, Italy
                [184 ]ISNI 0000 0001 2157 0617, GRID grid.39953.35, Indian Statistical Institute, ; Kolkata, India
                [185 ]Tabriz Health Services Management Centre, Tabriz, Iran
                [186 ]Sciensano, Brussels, Belgium
                [187 ]ISNI 0000000404654431, GRID grid.5650.6, Academic Medical Center of University of Amsterdam, ; Amsterdam, The Netherlands
                [188 ]ISNI 0000 0004 0619 7019, GRID grid.466934.a, National Research Centre for Preventive Medicine, ; Moscow, Russia
                [189 ]ISNI 000000040459992X, GRID grid.5645.2, Erasmus Medical Center Rotterdam, ; Rotterdam, The Netherlands
                [190 ]ISNI 0000 0001 2292 3357, GRID grid.14848.31, University of Montreal, Montreal, ; Québec, Canada
                [191 ]ISNI 0000000122879528, GRID grid.4399.7, Institut de Recherche pour le Développement, ; Montpellier, France
                [192 ]French Public Health Agency, St Maurice, France
                [193 ]Mediterranea Cardiocentro, Naples, Italy
                [194 ]ISNI 0000 0001 1882 7290, GRID grid.412302.6, Universidade do Vale do Rio dos Sinos, ; São Leopoldo, Brazil
                [195 ]ISNI 0000 0001 1945 2152, GRID grid.423606.5, National Council of Scientific and Technical Research, ; Tandil, Argentina
                [196 ]ISNI 0000 0004 0612 272X, GRID grid.415814.d, Ministry of Health and Medical Education, ; Tehran, Iran
                [197 ]GRID grid.419608.2, National Institute of Nutrition, ; Hanoi, Vietnam
                [198 ]ISNI 0000 0000 9320 7537, GRID grid.1003.2, University of Queensland, ; Brisbane, Queensland Australia
                [199 ]ISNI 0000 0000 9120 6856, GRID grid.416651.1, Istituto Superiore di Sanità, ; Rome, Italy
                [200 ]GRID grid.442123.2, Universidad de Cuenca, ; Cuenca, Ecuador
                [201 ]ISNI 0000 0004 0483 2525, GRID grid.4567.0, Helmholtz Zentrum München, ; Munich, Germany
                [202 ]GRID grid.463216.4, Ministère de la Santé et de la Lutte Contre le Sida, ; Abidjan, Côte d’Ivoire
                [203 ]GRID grid.418887.a, The Cardinal Wyszynski Institute of Cardiology, ; Warsaw, Poland
                [204 ]ISNI 0000 0000 8803 2373, GRID grid.198530.6, Beijing Center for Disease Prevention and Control, ; Beijing, China
                [205 ]ISNI 0000 0000 9011 8547, GRID grid.239395.7, BIDMC, ; Boston, MA USA
                [206 ]ISNI 0000 0001 0775 3222, GRID grid.9845.0, University of Latvia, ; Riga, Latvia
                [207 ]Ministry of Health and Medical Services, Gizo, Solomon Islands
                [208 ]ISNI 0000 0001 2218 219X, GRID grid.413068.8, University of Benin, ; Benin City, Nigeria
                [209 ]ISNI 0000 0001 2254 0954, GRID grid.412798.1, University of Skövde, ; Skövde, Sweden
                [210 ]National Institute of Nutrition and Food Technology, Tunis, Tunisia
                [211 ]ISNI 0000 0000 8786 7651, GRID grid.461576.7, The University of the West Indies, ; Kingston, Jamaica
                [212 ]ISNI 0000 0004 1936 9684, GRID grid.27860.3b, University of California Davis, ; Davis, CA USA
                [213 ]ISNI 0000 0001 2214 904X, GRID grid.11956.3a, University of Stellenbosch, ; Cape Town, South Africa
                [214 ]ISNI 0000 0001 1013 0499, GRID grid.14758.3f, National Institute for Health and Welfare, ; Helsinki, Finland
                [215 ]ISNI 0000 0004 0374 7521, GRID grid.4777.3, Queen’s University of Belfast, ; Belfast, UK
                [216 ]ISNI 0000 0000 8819 4698, GRID grid.412571.4, Shiraz University of Medical Sciences, ; Shiraz, Iran
                [217 ]Centro de Salud Villanueva Norte, Badajoz, Spain
                [218 ]Hospital Don Benito-Villanueva de la Serena, Badajoz, Spain
                [219 ]ISNI 0000 0001 2152 8611, GRID grid.452551.2, Ministry of Health, ; Buenos Aires, Argentina
                [220 ]ISNI 0000 0001 2293 6756, GRID grid.423616.4, Council for Agricultural Research and Economics, ; Rome, Italy
                [221 ]ISNI 0000 0001 2157 0406, GRID grid.7870.8, Pontificia Universidad Católica de Chile, ; Santiago, Chile
                [222 ]ISNI 0000 0004 0621 4763, GRID grid.418838.e, Institute of Mother and Child, ; Warsaw, Poland
                [223 ]ISNI 0000 0004 1937 0642, GRID grid.6612.3, University of Basel, ; Basel, Switzerland
                [224 ]ISNI 0000 0004 0587 0574, GRID grid.416786.a, Swiss TPH, ; Basel, Switzerland
                [225 ]ISNI 0000 0001 0943 7661, GRID grid.10939.32, University of Tartu, ; Tartu, Estonia
                [226 ]ISNI 0000 0004 1773 4764, GRID grid.415771.1, Instituto Nacional de Salud Pública, ; Cuernavaca, Mexico
                [227 ]ISNI 0000 0001 2294 3534, GRID grid.11875.3a, Universiti Sains Malaysia, ; Kelantan, Malaysia
                [228 ]ISNI 0000 0001 1034 3451, GRID grid.12650.30, Umeå University, ; Umeå, Sweden
                [229 ]ISNI 0000 0001 2106 8344, GRID grid.411672.7, Georgia College and State University, ; Milledgeville, GA USA
                [230 ]ISNI 0000 0001 0514 7202, GRID grid.411249.b, Federal University of São Paulo, ; São Paulo, Brazil
                [231 ]ISNI 0000 0004 1796 5984, GRID grid.411164.7, Hospital Universitario Son Espases, ; Palma, Spain
                [232 ]ISNI 0000 0001 0125 3761, GRID grid.414449.8, Hospital de Clinicas de Porto Alegre, ; Porto Alegre, Brazil
                [233 ]ISNI 0000 0001 2200 7498, GRID grid.8532.c, Universidade Federal do Rio Grande do Sul, ; Porto Alegre, Brazil
                [234 ]ISNI 0000 0004 1936 9967, GRID grid.258622.9, Kindai University, ; Osaka-Sayama, Japan
                [235 ]ISNI 0000 0004 0372 2033, GRID grid.258799.8, Kyoto University, ; Kyoto, Japan
                [236 ]ISNI 0000000113287408, GRID grid.13339.3b, Medical University of Warsaw, ; Warsaw, Poland
                [237 ]ISNI 0000 0004 1756 9674, GRID grid.415788.7, Ministry of Health, ; Rome, Italy
                [238 ]ISNI 0000 0004 1757 1969, GRID grid.8158.4, University of Catania, ; Catania, Italy
                [239 ]ISNI 0000 0000 9314 1427, GRID grid.413448.e, CIBER en Epidemiología y Salud Pública, ; Alicante, Spain
                [240 ]GRID grid.488675.0, Africa Health Research Institute, ; Mtubatuba, South Africa
                [241 ]ISNI 0000 0001 0721 9812, GRID grid.150338.c, Geneva University Hospitals, ; Geneva, Switzerland
                [242 ]ISNI 0000 0000 9314 1427, GRID grid.413448.e, CIBER en Epidemiología y Salud Pública, ; Barcelona, Spain
                [243 ]ISNI 0000 0004 0374 7118, GRID grid.466572.4, Australian Bureau of Statistics, ; Canberra, Australian Capital Territory Australia
                [244 ]ISNI 0000 0001 2181 4888, GRID grid.8430.f, Universidade Federal de Minas Gerais, ; Belo Horizonte, Brazil
                [245 ]ISNI 0000 0001 0791 5666, GRID grid.4818.5, Wageningen University, ; Wageningen, The Netherlands
                [246 ]ISNI 0000000121724807, GRID grid.18147.3b, University of Insubria, ; Varese, Italy
                [247 ]ISNI 0000 0004 1936 7304, GRID grid.1010.0, University of Adelaide, ; Adelaide, South Australia Australia
                [248 ]ISNI 0000 0001 0930 2361, GRID grid.4514.4, Lund University, ; Lund, Sweden
                [249 ]ISNI 0000 0004 1937 052X, GRID grid.414840.d, Ministry of Health, ; Jerusalem, Israel
                [250 ]ISNI 0000 0004 1936 8649, GRID grid.14709.3b, McGill University, ; Montreal, Québec Canada
                [251 ]ISNI 0000 0001 2163 6057, GRID grid.440855.8, Universidad Autonoma de Santo Domingo, ; Santo Domingo, Dominican Republic
                [252 ]ISNI 0000 0001 2151 2978, GRID grid.5690.a, Universidad Politécnica de Madrid, ; Madrid, Spain
                [253 ]The Andes Clinic of Cardio-Metabolic Studies, Merida, Venezuela
                [254 ]ISNI 0000 0004 0461 1191, GRID grid.493388.d, Instituto Nacional de Higiene, Epidemiología y Microbiología, ; Havana, Cuba
                [255 ]ISNI 0000 0001 0807 4731, GRID grid.420634.7, Ministry of Health, ; Lisbon, Portugal
                [256 ]ISNI 0000 0001 2299 1368, GRID grid.418930.7, Institute for Clinical and Experimental Medicine, ; Prague, Czech Republic
                [257 ]ISNI 0000 0001 2232 2498, GRID grid.413923.e, Children’s Memorial Health Institute, ; Warsaw, Poland
                [258 ]ISNI 0000000109457005, GRID grid.4793.9, Aristotle University of Thessaloniki, ; Thessaloniki, Greece
                [259 ]ISNI 0000 0001 2162 9631, GRID grid.5522.0, Jagiellonian University Medical College, ; Kraków, Poland
                [260 ]National Center of Cardiovascular Diseases, Beijing, China
                [261 ]ISNI 0000 0004 1757 2064, GRID grid.8484.0, University of Ferrara, ; Ferrara, Italy
                [262 ]ISNI 0000 0000 9458 5898, GRID grid.420802.c, Icelandic Heart Association, ; Kopavogur, Iceland
                [263 ]ISNI 0000 0000 9702 069X, GRID grid.440787.8, Universidad Icesi, ; Cali, Colombia
                [264 ]ISNI 0000 0004 0384 3767, GRID grid.412322.4, State University of Montes Claros, ; Montes Claros, Brazil
                [265 ]ISNI 0000 0001 2322 6764, GRID grid.13097.3c, King’s College London, ; London, UK
                [266 ]ISNI 0000000405980095, GRID grid.17703.32, International Agency for Research on Cancer, ; Lyon, France
                [267 ]ISNI 0000 0004 0369 153X, GRID grid.24696.3f, Capital Medical University, ; Beijing, China
                [268 ]ISNI 0000 0004 1760 4062, GRID grid.452712.7, Healis-Sekhsaria Institute for Public Health, ; Navi Mumbai, India
                [269 ]Eternal Heart Care Centre and Research Institute, Jaipur, India
                [270 ]ISNI 0000 0004 1794 5983, GRID grid.9582.6, University of Ibadan, ; Ibadan, Nigeria
                [271 ]ISNI 0000 0004 0439 4692, GRID grid.414661.0, Institute for Clinical Effectiveness and Health Policy, ; Buenos Aires, Argentina
                [272 ]Research and Education Institute of Child Health, Nicosia, Cyprus
                [273 ]ISNI 0000 0001 2175 6024, GRID grid.417390.8, Danish Cancer Society Research Centre, ; Copenhagen, Denmark
                [274 ]ISNI 0000 0000 9825 1537, GRID grid.465841.a, Alexander Technological Educational Institute, ; Thessaloniki, Greece
                [275 ]ISNI 0000 0001 2242 4849, GRID grid.177174.3, Kyushu University, ; Fukuoka, Japan
                [276 ]ISNI 0000 0004 1936 7443, GRID grid.7914.b, University of Bergen, ; Bergen, Norway
                [277 ]ISNI 0000 0001 2217 8588, GRID grid.265219.b, Tulane University, ; New Orleans, LA USA
                [278 ]ISNI 0000 0000 8803 2373, GRID grid.198530.6, Chinese Center for Disease Control and Prevention, ; Beijing, China
                [279 ]ISNI 0000 0001 0663 9479, GRID grid.9679.1, University of Pécs, ; Pécs, Hungary
                [280 ]Danish Health Authority, Copenhagen, Denmark
                [281 ]Joep Lange Institute, Amsterdam, The Netherlands
                [282 ]ISNI 0000 0004 4685 4917, GRID grid.412326.0, Oulu University Hospital, ; Oulu, Finland
                [283 ]ISNI 0000 0001 2296 8512, GRID grid.252609.a, Universidad Autónoma de Bucaramanga, ; Bucaramanga, Colombia
                [284 ]ISNI 0000 0001 2156 2780, GRID grid.5801.c, ETH Zurich, ; Zurich, Switzerland
                [285 ]Chronic Diseases Research Center, Tehran, Iran
                [286 ]ISNI 0000000121742757, GRID grid.194645.b, University of Hong Kong, ; Hong Kong, China
                [287 ]ISNI 0000 0004 1937 0482, GRID grid.10784.3a, The Chinese University of Hong Kong, ; Hong Kong, China
                [288 ]ISNI 0000 0004 1936 7910, GRID grid.1012.2, University of Western Australia, ; Perth, Western Australia Australia
                [289 ]Kingston Health Sciences Centre, Kingston, Ontario, Canada
                [290 ]ISNI 0000 0001 2297 2036, GRID grid.411074.7, Heart Institute, ; São Paulo, Brazil
                [291 ]Fundación Oftalmológica de Santander, Santander, Colombia
                [292 ]ISNI 0000 0001 2347 0804, GRID grid.440479.a, University Oran 1, ; Oran, Algeria
                [293 ]Independent Public Health Specialist, Nay Pyi Taw, Myanmar
                [294 ]GRID grid.500538.b, Ministry of Health and Sports, ; Nay Pyi Taw, Myanmar
                [295 ]ISNI 0000 0001 2256 9319, GRID grid.11135.37, Peking University, ; Beijing, China
                [296 ]ISNI 0000 0000 9314 1427, GRID grid.413448.e, CIBER en Epidemiología y Salud Pública, ; Murcia, Spain
                [297 ]ISNI 0000000084992262, GRID grid.7177.6, Amsterdam UMC of University of Amsterdam, ; Amsterdam, The Netherlands
                [298 ]ISNI 0000 0004 1754 9227, GRID grid.12380.38, Vrije Universiteit Amsterdam, ; Amsterdam, The Netherlands
                [299 ]ISNI 0000 0004 1936 9801, GRID grid.22903.3a, American University of Beirut, ; Beirut, Lebanon
                [300 ]ISNI 0000 0000 9314 1427, GRID grid.413448.e, CIBER en Epidemiología y Salud Pública, ; San Sebastian, Spain
                [301 ]ISNI 0000 0004 0639 9286, GRID grid.7776.1, Cairo University, ; Cairo, Egypt
                [302 ]ISNI 0000 0001 2151 536X, GRID grid.26999.3d, The University of Tokyo, ; Tokyo, Japan
                [303 ]ISNI 0000 0004 0397 9648, GRID grid.412688.1, University Hospital Centre Zagreb, ; Zagreb, Croatia
                [304 ]ISNI 0000 0001 0671 5144, GRID grid.260975.f, Niigata University, ; Niigata, Japan
                [305 ]ISNI 0000 0001 2221 2926, GRID grid.17788.31, Hadassah University Medical Center, ; Jerusalem, Israel
                [306 ]ISNI 0000 0001 1516 2393, GRID grid.5947.f, Norwegian University of Science and Technology, ; Trondheim, Norway
                [307 ]ISNI 0000 0001 2179 088X, GRID grid.1008.9, The University of Melbourne, Melbourne, ; Victoria, Australia
                [308 ]ISNI 0000 0001 2292 3330, GRID grid.12306.36, Sports University of Tirana, ; Tirana, Albania
                [309 ]ISNI 0000 0001 0657 4636, GRID grid.4808.4, University of Zagreb School of Medicine, ; Zagreb, Croatia
                [310 ]ISNI 0000 0004 0469 7714, GRID grid.453005.7, Heart Foundation, Melbourne, ; Victoria, Australia
                [311 ]GRID grid.454124.2, National Health Insurance Service, ; Wonju, South Korea
                [312 ]Guangzhou 12th Hospital, Guangzhou, China
                [313 ]GRID grid.441503.7, Universidad Eugenio Maria de Hostos, ; Santo Domingo, Dominican Republic
                [314 ]ISNI 0000 0004 1936 7494, GRID grid.61971.38, Simon Fraser University, ; Burnaby, British Columbia Canada
                [315 ]ISNI 0000 0001 2190 4373, GRID grid.7700.0, Ruprecht-Karls-University of Heidelberg, ; Heidelberg, Germany
                [316 ]GRID grid.417256.3, World Health Organization Country Office, ; Delhi, India
                [317 ]Institute of Public Health of Serbia, Belgrade, Serbia
                [318 ]ISNI 0000 0001 1010 7301, GRID grid.107891.6, University of Opole, ; Opole, Poland
                [319 ]ISNI 0000 0004 0576 3437, GRID grid.8127.c, University of Crete, ; Heraklion, Greece
                [320 ]ISNI 0000 0004 1937 1557, GRID grid.412113.4, Universiti Kebangsaan Malaysia, ; Kuala Lumpur, Malaysia
                [321 ]Hellenic Medical Association for Obesity, Athens, Greece
                [322 ]Maharajgunj Medical Campus, Kathmandu, Nepal
                [323 ]ISNI 0000 0001 1956 2722, GRID grid.7048.b, Aarhus University, ; Aarhus, Denmark
                [324 ]ISNI 0000 0001 2171 9311, GRID grid.21107.35, Johns Hopkins Bloomberg School of Public Health, ; Baltimore, MD USA
                [325 ]ISNI 0000 0001 2159 6024, GRID grid.250514.7, Pennington Biomedical Research Center, ; Baton Rouge, LA USA
                [326 ]ISNI 0000 0001 0726 2490, GRID grid.9668.1, University of Eastern Finland, ; Kuopio, Finland
                [327 ]ISNI 0000 0004 1767 6269, GRID grid.419587.6, National Institute of Epidemiology, ; Chennai, India
                [328 ]ISNI 0000 0001 2172 9288, GRID grid.5949.1, University of Münster, ; Münster, Germany
                [329 ]Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan, Iran
                [330 ]ISNI 0000 0004 0435 165X, GRID grid.16872.3a, Amsterdam Public Health Research Institute, ; Amsterdam, The Netherlands
                [331 ]GRID grid.444253.0, Kyrgyz State Medical Academy, ; Bishkek, Kyrgyzstan
                [332 ]ISNI 0000 0004 0551 0667, GRID grid.417942.d, Research Institute of Child Nutrition, ; Dortmund, Germany
                [333 ]ISNI 0000000121885934, GRID grid.5335.0, University of Cambridge, ; Cambridge, UK
                [334 ]Hypertension Research Center, Isfahan, Iran
                [335 ]ISNI 0000 0000 8853 2677, GRID grid.5361.1, Medical University of Innsbruck, ; Innsbruck, Austria
                [336 ]ISNI 0000 0001 1481 7466, GRID grid.25867.3e, Muhimbili University of Health and Allied Sciences, ; Dar es Salaam, Tanzania
                [337 ]ISNI 0000 0004 0628 9810, GRID grid.410914.9, National Cancer Center, ; Goyang-si, South Korea
                [338 ]ISNI 0000 0001 1090 0609, GRID grid.473016.7, Statistics Austria, ; Vienna, Austria
                [339 ]ISNI 0000 0004 1794 1501, GRID grid.414128.a, B. P. Koirala Institute of Health Sciences, ; Dharan, Nepal
                [340 ]ISNI 0000 0001 2286 1424, GRID grid.10420.37, University of Vienna, ; Vienna, Austria
                [341 ]ISNI 0000 0004 0450 4652, GRID grid.417779.b, Oulu Deaconess Institute Foundation, ; Oulu, Finland
                [342 ]ISNI 0000 0001 0943 7661, GRID grid.10939.32, Tartu University Clinics, ; Tartu, Estonia
                [343 ]ISNI 0000 0001 2172 5041, GRID grid.410783.9, Kansai Medical University, ; Osaka-Sayama, Japan
                [344 ]National Institute of Pharmacy and Nutrition, Budapest, Hungary
                [345 ]GRID grid.490650.e, Ministry of Health and Quality of Life, ; Port Louis, Mauritius
                [346 ]ISNI 0000 0001 1958 0162, GRID grid.413454.3, Polish Academy of Sciences Anthropology Unit, ; Wroclaw, Poland
                [347 ]GRID grid.410712.1, University Hospital Ulm, ; Ulm, Germany
                [348 ]ISNI 0000 0004 0407 1981, GRID grid.4830.f, University of Groningen, ; Groningen, The Netherlands
                [349 ]ISNI 0000 0000 9769 2525, GRID grid.25881.36, North-West University, ; Potchefstroom, South Africa
                [350 ]ISNI 0000 0001 2184 1595, GRID grid.425485.a, National Institute of Public Health, ; Prague, Czech Republic
                [351 ]ISNI 0000 0001 1013 7965, GRID grid.9681.6, University of Jyväskylä, ; Jyväskylä, Finland
                [352 ]Institute of Public Health of Montenegro, Podgorica, Montenegro
                [353 ]ISNI 0000 0004 1766 1016, GRID grid.427788.6, Amrita Institute of Medical Sciences, ; Cochin, India
                [354 ]ISNI 0000 0001 0833 2673, GRID grid.418976.5, Institute of Endocrinology, ; Prague, Czech Republic
                [355 ]ISNI 0000 0004 1767 6103, GRID grid.413618.9, All India Institute of Medical Sciences, ; New Delhi, India
                [356 ]ISNI 0000 0001 2221 4219, GRID grid.413355.5, African Population and Health Research Center, ; Nairobi, Kenya
                [357 ]GRID grid.448980.9, Hanoi University of Public Health, ; Hanoi, Vietnam
                [358 ]Higher Institute of Nursing Professions and Technical Health, Rabat, Morocco
                [359 ]National Institute of Public Health of Algeria, Algiers, Algeria
                [360 ]ISNI 0000 0000 8878 5439, GRID grid.413299.4, Croatian National Institute of Public Health, ; Zagreb, Croatia
                [361 ]ISNI 0000 0000 9919 9582, GRID grid.8761.8, Sahlgrenska Academy, ; Gothenburg, Sweden
                [362 ]ISNI 0000 0001 0166 0922, GRID grid.411705.6, Endocrinology and Metabolism Research Center, ; Tehran, Iran
                [363 ]GRID grid.449848.d, University of Public Health, ; Yangon, Myanmar
                [364 ]International Food Policy Research Institute, Dakar, Senegal
                [365 ]ISNI 0000 0001 2180 6431, GRID grid.4280.e, National University of Singapore, ; Singapore, Singapore
                [366 ]ISNI 0000 0004 1764 6123, GRID grid.16890.36, Hong Kong Polytechnic University, ; Hong Kong, China
                [367 ]ISNI 0000 0004 0628 2985, GRID grid.412330.7, Tampere University Hospital, ; Tampere, Finland
                [368 ]ISNI 0000 0001 2107 607X, GRID grid.413096.9, University of Douala, ; Douala, Cameroon
                [369 ]ISNI 0000 0004 1937 1151, GRID grid.7836.a, University of Cape Town, ; Cape Town, South Africa
                [370 ]ISNI 0000 0001 2156 6140, GRID grid.268154.c, West Virginia University, ; Morgantown, WV USA
                [371 ]ISNI 0000 0001 0723 0931, GRID grid.418068.3, Oswaldo Cruz Foundation Rene Rachou Research Institute, ; Belo Horizonte, Brazil
                [372 ]ISNI 0000 0004 0546 0241, GRID grid.19188.39, National Taiwan University, ; Taipei, Taiwan
                [373 ]ISNI 0000 0004 1797 8419, GRID grid.410726.6, University of Chinese Academy of Sciences, ; Shanghai, China
                [374 ]ISNI 0000 0004 1936 9457, GRID grid.8993.b, Uppsala University, ; Uppsala, Sweden
                [375 ]ISNI 0000 0004 0369 153X, GRID grid.24696.3f, Capital Medical University Beijing An Zhen Hospital, ; Beijing, China
                [376 ]GRID grid.416712.7, National Institute for Health Development, ; Tallinn, Estonia
                [377 ]GRID grid.441816.e, Universidad San Martín de Porres, ; Lima, Peru
                [378 ]GRID grid.5603.0, University Medicine of Greifswald, ; Greifswald, Germany
                [379 ]ISNI 0000 0001 2192 6054, GRID grid.454835.b, Consejería de Sanidad Junta de Castilla y León, ; Valladolid, Spain
                [380 ]ISNI 0000 0001 0326 8799, GRID grid.436605.2, Norrbotten County Council, ; Luleå, Sweden
                [381 ]ISNI 0000 0004 1936 9457, GRID grid.8993.b, University of Uppsala, ; Uppsala, Sweden
                [382 ]ISNI 0000 0004 0488 4317, GRID grid.411213.4, Universidade Federal de Ouro Preto, ; Ouro Preto, Brazil
                [383 ]ISNI 0000 0000 9511 4342, GRID grid.8051.c, University of Coimbra, ; Coimbra, Portugal
                [384 ]ISNI 0000 0001 0661 2073, GRID grid.411898.d, The Jikei University School of Medicine, ; Tokyo, Japan
                [385 ]ISNI 0000 0001 1940 4177, GRID grid.5326.2, National Research Council, ; Padua, Italy
                [386 ]ISNI 0000 0000 9760 5620, GRID grid.1051.5, Baker Heart and Diabetes Institute, Melbourne, ; Victoria, Australia
                [387 ]ISNI 0000 0001 0794 1186, GRID grid.10985.35, Agricultural University of Athens, ; Athens, Greece
                [388 ]ISNI 0000 0001 0385 1941, GRID grid.413562.7, Hospital Israelita Albert Einstein, ; São Paulo, Brazil
                [389 ]Institute of Internal and Preventive Medicine, Novosibirsk, Russia
                [390 ]ISNI 0000 0004 0622 2843, GRID grid.15823.3d, Harokopio University, ; Athens, Greece
                [391 ]ISNI 0000 0004 1936 7830, GRID grid.29980.3a, University of Otago, ; Dunedin, New Zealand
                [392 ]ISNI 0000 0004 1757 3470, GRID grid.5608.b, University of Padua, ; Padua, Italy
                [393 ]ISNI 0000 0004 0393 8299, GRID grid.419879.a, Technological Educational Institute of Crete, ; Heraklion, Greece
                [394 ]ISNI 0000 0004 1936 8542, GRID grid.6571.5, Loughborough University, ; Loughborough, UK
                [395 ]GRID grid.426504.1, Ministry of Health, ; Nicosia, Cyprus
                [396 ]ISNI 0000 0001 0423 4662, GRID grid.8515.9, Lausanne University Hospital, ; Lausanne, Switzerland
                [397 ]CIBERCV, Barcelona, Spain
                [398 ]ISNI 0000 0004 1936 9692, GRID grid.10049.3c, Mary Immaculate College, ; Limerick, Ireland
                [399 ]ISNI 0000 0001 0941 6502, GRID grid.189967.8, Emory University, ; Atlanta, GA USA
                [400 ]Hungarian Society of Sports Medicine, Budapest, Hungary
                [401 ]ISNI 0000 0001 0174 2901, GRID grid.414739.c, Sher-i-Kashmir Institute of Medical Sciences, ; Srinagar, India
                [402 ]ISNI 0000000122595234, GRID grid.10919.30, UiT The Arctic University of Norway, ; Tromsø, Norway
                [403 ]National Centre for Disease Informatics and Research, New Delhi, India
                [404 ]ISNI 0000 0001 0177 134X, GRID grid.411921.e, Cape Peninsula University of Technology, ; Cape Town, South Africa
                [405 ]ISNI 0000 0001 2154 3176, GRID grid.13856.39, University of Rzeszow, ; Rzeszow, Poland
                [406 ]ISNI 0000 0004 1936 7988, GRID grid.4305.2, University of Edinburgh, ; Edinburgh, UK
                [407 ]ISNI 0000 0000 8946 5787, GRID grid.411729.8, International Medical University, ; Shah Alam, Malaysia
                [408 ]GRID grid.457380.d, Institut National de la Santé et de la Recherche Médicale, ; Lille, France
                [409 ]ISNI 0000 0001 0940 3744, GRID grid.13652.33, Robert Koch Institute, ; Berlin, Germany
                [410 ]ISNI 0000 0000 8484 6281, GRID grid.164242.7, Lusófona University, ; Lisbon, Portugal
                [411 ]ISNI 0000 0001 2170 8022, GRID grid.12284.3d, Democritus University, ; Alexandroupolis, Greece
                [412 ]ISNI 0000 0001 0685 1605, GRID grid.411038.f, Grigore T. Popa University of Medicine and Pharmacy, ; Iasi, Romania
                [413 ]ISNI 0000 0004 1757 2304, GRID grid.8404.8, Università degli Studi di Firenze, ; Florence, Italy
                [414 ]ISNI 0000 0001 1498 685X, GRID grid.411036.1, Isfahan Cardiovascular Research Center, ; Isfahan, Iran
                [415 ]ISNI 0000 0001 2177 138X, GRID grid.412220.7, Strasbourg University Hospital, ; Strasbourg, France
                [416 ]ISNI 0000 0001 2157 9291, GRID grid.11843.3f, University of Strasbourg, ; Strasbourg, France
                [417 ]ISNI 0000 0000 9634 2734, GRID grid.416252.6, Mulago Hospital, ; Kampala, Uganda
                [418 ]ISNI 0000 0004 1773 4764, GRID grid.415771.1, Instituto Nacional de Salud Pública, ; Mexico City, Mexico
                [419 ]ISNI 0000 0001 2105 2799, GRID grid.411732.2, University of Limpopo, ; Sovenga, South Africa
                [420 ]ISNI 0000 0004 0484 7305, GRID grid.412482.9, Seoul National University Children’s Hospital, ; Seoul, South Korea
                [421 ]University Medical Science, Havana, Cuba
                [422 ]ISNI 0000 0001 2152 8769, GRID grid.11205.37, Universidad de Zaragoza, ; Zaragoza, Spain
                [423 ]ISNI 0000 0004 0488 7120, GRID grid.4912.e, RCSI, ; Dublin, Ireland
                [424 ]ISNI 0000 0001 2342 0938, GRID grid.1018.8, La Trobe University, ; Melbourne, Victoria Australia
                [425 ]GRID grid.419362.b, International Institute of Molecular and Cell Biology, ; Warsaw, Poland
                [426 ]ISNI 0000 0000 9296 6873, GRID grid.411230.5, Ahvaz Jundishapur University of Medical Sciences, ; Ahvaz, Iran
                [427 ]Gorgas Memorial Institute of Public Health, Panama City, Panama
                [428 ]World Health Organization Country Office, Lilongwe, Malawi
                [429 ]Department of Public Health, Nay Pyi Taw, Myanmar
                [430 ]ISNI 0000000417571846, GRID grid.7637.5, University of Brescia, ; Brescia, Italy
                [431 ]Ministry of Health and Social Protection, Dushanbe, Tajikistan
                [432 ]GRID grid.411832.d, Bushehr University of Medical Sciences, ; Bushehr, Iran
                [433 ]ISNI 0000 0004 1936 9748, GRID grid.6582.9, Ulm University, ; Ulm, Germany
                [434 ]ISNI 0000 0001 1092 3077, GRID grid.31432.37, Kobe University, ; Kobe, Japan
                [435 ]ISNI 0000 0004 1801 630X, GRID grid.419712.8, Suraj Eye Institute, ; Nagpur, India
                [436 ]UNICEF, Yaoundé, Cameroon
                [437 ]ISNI 0000 0000 8955 7323, GRID grid.419597.7, National Institute of Hygiene and Epidemiology, ; Hanoi, Vietnam
                [438 ]University of Pharmacy and Medicine, Ho Chi Minh City, Vietnam
                [439 ]ISNI 0000 0004 0642 8489, GRID grid.56046.31, Hanoi Medical University, ; Hanoi, Vietnam
                [440 ]Miami Veterans Affairs Healthcare System, Miami, FL USA
                [441 ]Heartfile, Islamabad, Pakistan
                [442 ]ISNI 0000 0001 2168 5385, GRID grid.272242.3, National Cancer Center, ; Tokyo, Japan
                [443 ]Eastern Mediterranean Public Health Network, Amman, Jordan
                [444 ]ISNI 0000 0004 0401 2738, GRID grid.28224.3e, State University of Medicine and Pharmacy, ; Chisinau, Moldova
                [445 ]ISNI 0000 0004 0531 5386, GRID grid.416822.b, Tachikawa General Hospital, ; Nagaoka, Japan
                [446 ]Japan Wildlife Research Center, Tokyo, Japan
                [447 ]University of Vale do Rio dos Sinos, São Leopoldo, Brazil
                [448 ]ISNI 0000 0001 0744 1632, GRID grid.419363.a, National Food and Nutrition Institute, ; Warsaw, Poland
                [449 ]ISNI 0000000121662407, GRID grid.5379.8, University of Manchester, ; Manchester, UK
                [450 ]Ministry of Health, Bandar Seri Begawan, Brunei Darussalam
                [451 ]ISNI 0000 0001 2155 1272, GRID grid.26793.39, University of Madeira, ; Funchal, Portugal
                [452 ]ISNI 0000 0004 0462 1680, GRID grid.267033.3, University of Puerto Rico, ; San Juan, Puerto Rico
                [453 ]Research Center for Prevention and Health, Glostrup, Denmark
                [454 ]ISNI 0000 0004 0606 4099, GRID grid.451069.f, MRC Lifecourse Epidemiology Unit, ; Southampton, UK
                [455 ]ISNI 0000 0001 2149 743X, GRID grid.10822.39, University of Novi Sad, ; Novi Sad, Serbia
                [456 ]ISNI 0000000109466120, GRID grid.9829.a, Kwame Nkrumah University of Science and Technology, ; Kumasi, Ghana
                [457 ]GRID grid.482968.9, Institute for Social and Preventive Medicine, ; Lausanne, Switzerland
                [458 ]ISNI 0000 0000 9324 4864, GRID grid.429138.5, Cancer Prevention and Research Institute, ; Florence, Italy
                [459 ]ISNI 0000 0001 2167 3675, GRID grid.14003.36, University of Wisconsin-Madison, ; Madison, WI USA
                [460 ]ISNI 0000 0004 1757 9135, GRID grid.413503.0, IRCCS Casa Sollievo della Sofferenza, ; Bari, Italy
                [461 ]GRID grid.444464.2, Zayed University, ; Abu Dhabi, United Arab Emirates
                [462 ]ISNI 0000 0000 9370 7312, GRID grid.253755.3, Catholic University of Daegu, ; Daegu, South Korea
                [463 ]University of Medicine, Pharmacy, Science and Technology of Târgu Mureş, Târgu Mureş, Romania
                [464 ]Jivandeep Hospital, Anand, India
                [465 ]ISNI 0000 0000 9155 0024, GRID grid.415021.3, South African Medical Research Council, ; Durban, South Africa
                [466 ]Spanish Food Safety and Nutrition Agency, Madrid, Spain
                [467 ]ISNI 0000 0004 4691 4377, GRID grid.414163.5, Vietnam National Heart Institute, ; Hanoi, Vietnam
                [468 ]ISNI 0000 0000 9750 3253, GRID grid.418465.a, Leibniz Institute for Prevention Research and Epidemiology - BIPS, ; Bremen, Germany
                [469 ]ISNI 0000000121848551, GRID grid.11869.37, University of Sarajevo, ; Sarajevo, Bosnia and Herzegovina
                [470 ]Cardiovascular Prevention Centre Udine, Udine, Italy
                [471 ]ISNI 0000 0004 1756 8209, GRID grid.144189.1, University Hospital of Pisa, ; Pisa, Italy
                [472 ]Ministry of Health and Medical Services, Honiara, Solomon Islands
                [473 ]GRID grid.500777.2, Public Health Agency of Catalonia, ; Barcelona, Spain
                [474 ]ISNI 0000 0004 1767 9005, GRID grid.20522.37, Institut Hospital del Mar d’Investigacions Mèdiques, ; Barcelona, Spain
                [475 ]Digestive Oncology Research Center, Tehran, Iran
                [476 ]Digestive Disease Research Institute, Tehran, Iran
                [477 ]Centre for Disease Prevention and Control, Riga, Latvia
                [478 ]ISNI 0000 0001 0166 0922, GRID grid.411705.6, Alborz University of Medical Sciences, ; Karaj, Iran
                [479 ]GRID grid.67122.30, Ministry of Health, ; Hanoi, Vietnam
                [480 ]ISNI 0000 0001 0745 3561, GRID grid.501438.b, BRAC, ; Dhaka, Bangladesh
                [481 ]ISNI 0000 0004 0455 1600, GRID grid.502825.8, Institute of Epidemiology Disease Control and Research, ; Dhaka, Bangladesh
                [482 ]ISNI 0000 0001 2097 1371, GRID grid.1374.1, University of Turku, ; Turku, Finland
                [483 ]GRID grid.452479.9, Institut Universitari d’Investigació en Atenció Primària Jordi Gol, ; Girona, Spain
                [484 ]ISNI 0000 0001 2231 800X, GRID grid.11142.37, Universiti Putra Malaysia, ; Serdang, Malaysia
                [485 ]ISNI 0000 0001 2308 5949, GRID grid.10347.31, University of Malaya, ; Kuala Lumpur, Malaysia
                [486 ]GRID grid.459286.4, National Institute of Public Health, ; Copenhagen, Denmark
                [487 ]ISNI 0000 0001 2173 938X, GRID grid.5338.d, University of Valencia, ; Valencia, Spain
                [488 ]ISNI 0000 0000 9650 2179, GRID grid.11159.3d, University of the Philippines, ; Manila, The Philippines
                [489 ]ISNI 0000 0001 2180 9405, GRID grid.419303.c, Slovak Academy of Sciences, ; Bratislava, Slovakia
                [490 ]Nutrition Research Foundation, Barcelona, Spain
                [491 ]Minas Gerais State Secretariat for Health, Belo Horizonte, Brazil
                [492 ]Health Center San Agustín, Palma, Spain
                [493 ]GRID grid.487140.e, PharmAccess Foundation, ; Amsterdam, The Netherlands
                [494 ]ISNI 0000 0001 2287 695X, GRID grid.422270.1, National Institute of Health Doutor Ricardo Jorge, ; Lisbon, Portugal
                [495 ]ISNI 0000 0004 0414 8221, GRID grid.412295.9, Universidade Nove de Julho, ; São Paulo, Brazil
                [496 ]ISNI 0000 0001 0805 4386, GRID grid.415368.d, Public Health Agency of Canada, ; Ottawa, Ontario Canada
                [497 ]Canarian Health Service, Tenerife, Spain
                [498 ]ISNI 0000 0001 2105 7207, GRID grid.411595.d, Universidad Industrial de Santander, ; Santander, Colombia
                [499 ]ISNI 000000009445082X, GRID grid.1649.a, Sahlgrenska University Hospital, ; Gothenburg, Sweden
                [500 ]ISNI 0000 0004 0455 8044, GRID grid.417863.f, Fiji National University, ; Suva, Fiji
                [501 ]Spanish Nutrition Foundation, Madrid, Spain
                [502 ]ISNI 0000 0004 1781 0819, GRID grid.429574.9, Institute of Food Sciences of the National Research Council, ; Avellino, Italy
                [503 ]ISNI 0000 0001 0706 4670, GRID grid.272555.2, Singapore Eye Research Institute, ; Singapore, Singapore
                [504 ]ISNI 0000 0001 0740 0996, GRID grid.419277.e, Sitaram Bhartia Institute of Science and Research, ; New Delhi, India
                [505 ]GRID grid.449862.5, Maragheh University of Medical Sciences, ; Maragheh, Iran
                [506 ]ISNI 0000 0004 0410 2071, GRID grid.7737.4, University of Helsinki, ; Helsinki, Finland
                [507 ]National Institute of Health, Lima, Peru
                [508 ]ISNI 0000 0004 0470 8161, GRID grid.415709.e, Ministry of Health, ; Jakarta, Indonesia
                [509 ]Catalan Department of Health, Barcelona, Spain
                [510 ]GRID grid.432380.e, Biodonostia Health Research Institute, ; San Sebastian, Spain
                [511 ]ISNI 0000 0001 2181 4263, GRID grid.9983.b, Universidade de Lisboa, ; Lisbon, Portugal
                [512 ]ISNI 0000 0004 0570 4226, GRID grid.434312.3, South Karelia Social and Health Care District, ; Lappeenranta, Finland
                [513 ]Cardiovascular Research Institute, Isfahan, Iran
                [514 ]ISNI 0000 0004 1937 0722, GRID grid.11899.38, University of São Paulo Clinics Hospital, ; São Paulo, Brazil
                [515 ]ISNI 0000 0001 2319 4408, GRID grid.414775.4, Hospital Italiano de Buenos Aires, ; Buenos Aires, Argentina
                [516 ]ISNI 0000 0000 9259 8492, GRID grid.22937.3d, Medical University of Vienna, ; Vienna, Austria
                [517 ]GRID grid.475435.4, Rigshospitalet, ; Copenhagen, Denmark
                [518 ]ISNI 0000 0001 0725 8811, GRID grid.411276.7, Lagos State University College of Medicine, ; Lagos, Nigeria
                [519 ]ISNI 0000 0004 1769 9380, GRID grid.4521.2, University of Las Palmas de Gran Canaria, ; Las Palmas de Gran Canaria, Spain
                [520 ]ISNI 0000 0004 5345 9480, GRID grid.429654.8, National Center for Disease Control and Public Health, ; Tbilisi, Georgia
                [521 ]ISNI 0000 0004 0489 0290, GRID grid.45203.30, National Center for Global Health and Medicine, ; Tokyo, Japan
                [522 ]ISNI 0000 0001 0640 5613, GRID grid.414964.a, Samsung Medical Center, ; Seoul, South Korea
                [523 ]ISNI 0000 0000 9119 2677, GRID grid.437825.f, St Vincent’s Hospital, ; Sydney, New South Wales Australia
                [524 ]ISNI 0000 0004 4902 0432, GRID grid.1005.4, University of New South Wales, ; Sydney, New South Wales Australia
                [525 ]Health Polytechnic Jakarta II Institute, Jakarta, Indonesia
                [526 ]ISNI 0000 0001 0744 0787, GRID grid.412032.6, Diponegoro University, ; Semarang, Indonesia
                [527 ]ISNI 0000 0001 0120 3326, GRID grid.7644.1, University of Bari, ; Bari, Italy
                [528 ]Institut Régional de Santé Publique, Ouidah, Benin
                [529 ]ISNI 0000 0001 2106 639X, GRID grid.412041.2, University of Bordeaux, ; Bordeaux, France
                [530 ]Institute of Public Health, Skopje, Macedonia
                [531 ]ISNI 0000 0001 0668 7884, GRID grid.5596.f, University of Leuven, ; Leuven, Belgium
                [532 ]GRID grid.483025.8, Lamprecht und Stamm Sozialforschung und Beratung AG, ; Zurich, Switzerland
                [533 ]INSERM, Nancy, France
                [534 ]ISNI 0000 0001 2240 3300, GRID grid.10388.32, Bonn University, ; Bonn, Germany
                [535 ]GRID grid.416145.3, Sotiria Hospital, ; Sotiria, Greece
                [536 ]ISNI 0000 0001 1172 7414, GRID grid.415789.6, National Institute of Public Health-National Institute of Hygiene, ; Warsaw, Poland
                [537 ]ISNI 0000 0001 0658 8800, GRID grid.4827.9, Swansea University, ; Swansea, UK
                [538 ]ISNI 0000 0004 1937 1063, GRID grid.256105.5, Fu Jen Catholic University, ; Taipei, Taiwan
                [539 ]National Statistic Office of Cabo Verde, Praia, Cabo Verde
                [540 ]ISNI 0000 0001 0723 4123, GRID grid.16463.36, University of KwaZulu-Natal, ; Mtubatuba, South Africa
                [541 ]GRID grid.415773.3, Ministry of Health, ; Amman, Jordan
                [542 ]ISNI 0000000109409708, GRID grid.7634.6, Comenius University, ; Bratislava, Slovakia
                [543 ]Health Service of Murcia, Murcia, Spain
                [544 ]IB-SALUT Area de Salut de Menorca, Maó, Spain
                [545 ]ISNI 0000 0004 1757 1758, GRID grid.6292.f, University of Bologna, ; Bologna, Italy
                [546 ]GRID grid.424637.0, Hellenic Health Foundation, ; Athens, Greece
                [547 ]ISNI 0000 0004 1801 0602, GRID grid.413227.1, Government Medical College, ; Bhavnagar, India
                [548 ]ISNI 0000 0000 8637 3780, GRID grid.459957.3, Sefako Makgatho Health Science University, ; Ga-Rankuwa, South Africa
                [549 ]ISNI 0000 0001 1250 5688, GRID grid.7123.7, Addis Ababa University, ; Addis Ababa, Ethiopia
                [550 ]ISNI 0000 0004 0518 1285, GRID grid.452356.3, Dasman Diabetes Institute, ; Kuwait City, Kuwait
                [551 ]ISNI 0000 0004 0483 5988, GRID grid.415708.f, Ministry of Health, ; Wellington, New Zealand
                [552 ]ISNI 0000 0001 0666 9942, GRID grid.412877.f, Universidad Centro-Occidental Lisandro Alvarado, ; Barquisimeto, Venezuela
                [553 ]ISNI 0000 0001 0286 752X, GRID grid.259870.1, Meharry Medical College, ; Nashville, TN USA
                [554 ]ISNI 0000 0001 2183 9022, GRID grid.21200.31, Dokuz Eylul University, ; Izmir, Turkey
                [555 ]ISNI 0000 0001 2314 6254, GRID grid.502801.e, University of Tampere Tays Eye Center, ; Tampere, Finland
                [556 ]ISNI 0000 0001 2191 8636, GRID grid.410926.8, Polytechnic Institute of Porto, ; Porto, Portugal
                [557 ]ISNI 0000000120346234, GRID grid.5477.1, Utrecht University, ; Utrecht, The Netherlands
                [558 ]ISNI 0000000090126352, GRID grid.7692.a, University Medical Center Utrecht, ; Utrecht, The Netherlands
                [559 ]ISNI 0000 0001 1940 4177, GRID grid.5326.2, National Research Council, ; Pisa, Italy
                [560 ]ISNI 0000 0001 0586 4893, GRID grid.26811.3c, Universidad Miguel Hernandez, ; Alicante, Spain
                [561 ]GRID grid.450284.f, Ministry of Health, ; Mont Fleuri, Seychelles
                [562 ]North Karelian Center for Public Health, Joensuu, Finland
                [563 ]ISNI 0000 0004 1937 1135, GRID grid.11951.3d, University of the Witwatersrand, ; Johannesburg, South Africa
                [564 ]ISNI 0000 0001 0687 2000, GRID grid.414676.6, Institute for Medical Research, ; Kuala Lumpur, Malaysia
                [565 ]ISNI 0000 0004 1799 3993, GRID grid.13394.3c, Xinjiang Medical University, ; Urumqi, China
                [566 ]Shanghai Educational Development Co. Ltd, Shanghai, China
                [567 ]ISNI 0000 0004 0523 5263, GRID grid.21604.31, Paracelsus Medical University, ; Salzburg, Austria
                [568 ]ISNI 0000 0000 8546 682X, GRID grid.264200.2, St George’s, University of London, ; London, UK
                [569 ]ISNI 0000000120191471, GRID grid.9581.5, Universitas Indonesia, ; Jakarta, Indonesia
                [570 ]ISNI 0000 0004 0369 6250, GRID grid.418524.e, Institute of Food and Nutrition Development of Ministry of Agriculture, ; Beijing, China
                [571 ]ISNI 0000 0004 0407 2968, GRID grid.411333.7, Children’s Hospital of Fudan University, ; Shanghai, China
                [572 ]ISNI 0000000121167908, GRID grid.6603.3, University of Cyprus, ; Nicosia, Cyprus
                [573 ]ISNI 0000 0004 4911 7066, GRID grid.411746.1, Iran University of Medical Sciences, ; Tehran, Iran
                [574 ]West Kazakhstan State Medical University, Aktobe, Kazakhstan
                [575 ]ISNI 0000 0004 0604 6392, GRID grid.410612.0, Inner Mongolia Medical University, ; Hohhot, China
                Article
                1171
                10.1038/s41586-019-1171-x
                6784868
                31068725
                4664964b-a79b-4eac-b2d1-e432c45bbe8f
                © The Author(s) 2019

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 29 October 2018
                : 30 March 2019
                Categories
                Letter
                Custom metadata
                © The Author(s), under exclusive licence to Springer Nature Limited 2019

                Uncategorized
                risk factors,epidemiology
                Uncategorized
                risk factors, epidemiology

                Comments

                Comment on this article