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      PTEN and miR-26b: Promising prognostic biomarkers in initiation and progression of Oral Squamous Cell Carcinoma.

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          Abstract

          Oral Squamous Cell Carcinoma (OSCC) is the most common malignancy of the oral cavity. Phosphatase and TENsin homolog (PTEN) is a well-known tumor suppressive gene regulated by several biomarkers including a small single-stranded molecule, microRNA26b (miR-26b). Here, we studied the expression of PTEN and miR-26b in OSCC specimens in comparison with adjacent normal mucosa.

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          Author and article information

          Journal
          J. Oral Pathol. Med.
          Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
          Wiley
          1600-0714
          0904-2512
          Jan 2019
          : 48
          : 1
          Affiliations
          [1 ] Department of Oral and Maxillofacial Pathology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
          [2 ] Department of Pathology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
          [3 ] Cancer Biology Research Center, Iran National Tumor Bank, Cancer Institute Hospital, Tehran University of Medical Sciences, Tehran, Iran.
          [4 ] School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
          [5 ] Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
          Article
          10.1111/jop.12794
          30372795
          467124eb-b4d7-471f-8be5-0eb4db3969b7
          History

          microRNA, PTEN ,carcinoma,squamous cell of head and neck,MIRN26

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