Live Attenuated Pru:Δcdpk2 Strain of Toxoplasma gondii Protects Against Acute, Chronic, and Congenital Toxoplasmosis

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Abstract

The threat of Toxoplasma gondii infection in immunocompromised individuals and pregnant women necessitates the development of a safe and effective vaccine. Here, we examined the immune protection conferred by a live attenuated strain of T. gondii.

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Author and article information

Journal

Title: The Journal of Infectious Diseases

Publisher: Oxford University Press (OUP)

ISSN (Print): 0022-1899

ISSN (Electronic): 1537-6613

Publication date Created: September 01 2018

Publication date Created: July 24 2018

Publication date Created: April 13 2018

Publication date Other: September 01 2018

Publication date (Print): July 24 2018

Publication date (Electronic): April 13 2018

Volume: 218

Issue: 5

Pages: 768-777

Affiliations

[1 ]State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, People’s Republic of China

[2 ]Faculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, University of Nottingham, Loughborough, United Kingdom

[3 ]College of Marine Science, Shandong University at Weihai, Weihai, Shandong Province, People’s Republic of China

[4 ]College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi Province, People’s Republic of China

[5 ]Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu Province, People’s Republic of China

Article

DOI: 10.1093/infdis/jiy211

PubMed ID: 29669003

SO-VID: 467334fd-917d-40cb-9860-92cbe9f6d0db

License:

https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model

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