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      Comparison of oral amoxicillin with placebo for the treatment of world health organization-defined nonsevere pneumonia in children aged 2-59 months: a multicenter, double-blind, randomized, placebo-controlled trial in pakistan.

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          Abstract

          world Health Organization (WHO) acute respiratory illness case management guidelines classify children with fast breathing as having pneumonia and recommend treatment with an antibiotic. There is concern that many of these children may not have pneumonia and are receiving antibiotics unnecessarily. This could increase antibiotic resistance in the community. The aim was to compare the clinical outcome at 72 h in children with WHO-defined nonsevere pneumonia when treated with amoxicillin, compared with placebo.

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          Author and article information

          Journal
          Clin Infect Dis
          Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
          Oxford University Press (OUP)
          1537-6591
          1058-4838
          Feb 01 2011
          : 52
          : 3
          Affiliations
          [1 ] ARI Research Cell, Children's Hospital, Pakistan Institute of Medical Sciences, Pakistan. tabishhazir@hotmail.com
          Article
          ciq142
          10.1093/cid/ciq142
          21189270
          46b64d60-bdcd-457f-a854-d966a2c2f879
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