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      Rapid Detection of Cytomegalovirus DNA in Sera Using the Polymerase Chain Reaction: Relationship with Clinical Diagnosis of Cytomegalovirus Infection after Renal Transplantation

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          Abstract

          A 21-year-old man had chronic renal failure and received a renal transplant. We used the polymerase chain reaction technique to detect cytomegalovirus (CMV) DNA in serum, blood, and urine for the diagnosis of CMV infection after the renal transplantation. CMV DNA in the serum was detected by polymerase chain reaction only during the active stage, while CMV DNA in urine and blood was detected even during the silent stage of CMV infection. It is suggested that the use of the polymerase chain reaction in serum would be useful for the rapid diagnosis of active CMV infection.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1995
          1995
          18 December 2008
          : 70
          : 1
          : 100-103
          Affiliations
          Departments of aClinical Pathology and bInternal Medicine, Showa University Fujigaoka Hospital, Yokohama; cDepartment of Cell Regulation, Division of Virology and Immunology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan
          Article
          188551 Nephron 1995;70:100–103
          10.1159/000188551
          7617086
          © 1995 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 4
          Categories
          Case Report

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