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      Rest and Exercise Hemodynamic Studies in Patients with Isolated Aortic Stenosis

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      S. Karger AG

      Aortic valve gradient, Aortic valve flow, Aortic valve area

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          Hemodynamic data obtained during rest and exercise in 22 patients with aortic stenosis were analyzed. Mean aortic valve gradient for the group did not change significantly during exercise but there was large individual variability. Aortic valve flow increased during exercise in all but 2 patients. There was no correlation between change in gradient and change in flow during exercise. Although the mean calculated aortic valve area for the group did not change significantly during exercise, the calculated area was larger during exercise in most patients. Change in the calculated valve area correlated best with changes in aortic valve flow, left ventricular stroke work index, and the product of left ventricular systolic pressure and stroke volume. This suggests that in some patients there may be a dynamic component to aortic valve obstruction that may vary with changing hemodynamics.

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          Author and article information

          S. Karger AG
          31 October 2008
          : 64
          : 1
          : 1-11
          Department of Internal Medicine, University of Utah College of Medicine and Veterans Administration Hospital, Salt Lake City, Utah
          170573 Cardiology 1979;64:1–11
          © 1979 S. Karger AG, Basel

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          Pages: 11
          Original Paper


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