0
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found

      Reevaluation of the Pituitary-Adrenal Response to Ether in Rats with Various Cuts Around the Medial Basal Hypothalamus

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          ACTH release elicited by ether inhalation or ethervenesection and measured by changes in plasma corticosterone level was studied in rats at various time intervals after placing a complete or an anterolateral cut around the medial basal hypothalamus (MBH). There was no rise in ‘resting’ plasma corticosterone after acceptable isolations and, in 5 out of 6 series of experiments, the complete or long anterolateral cuts prevented the rise in plasma corticosterone normally induced by ether stress. In contrast, ethervenesection elicited a significant increment of plasma corticosterone when the basal region of the lateral retrochiasmatic area (RCAL) was not completely transected. Possible reasons why these experiments failed to confirm previous findings are discussed. These results support the hypothesis that corticoliberin-containing fibers enter the MBH from outside and that most of these fibers run through the RCAL on their way towards the neurohemal regions of the infundibulum.

          Related collections

          Author and article information

          Journal
          NEN
          Neuroendocrinology
          10.1159/issn.0028-3835
          Neuroendocrinology
          S. Karger AG
          0028-3835
          1423-0194
          1980
          1980
          26 March 2008
          : 30
          : 1
          : 38-44
          Affiliations
          Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest
          Article
          122972 Neuroendocrinology 1980;30:38–44
          10.1159/000122972
          6243756
          © 1980 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 7
          Categories
          Original Paper

          Comments

          Comment on this article