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      Ultrasonographic Evaluation of Cardiac and Vascular Changes in Young Borderline Hypertensives

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          Abstract

          We measured the intima-media thickness of the common carotid artery (CCA) and of its bifurcation (BIF) in 20 borderline hypertensives (age 24 ± 4 years) and in 20 normotensive subjects (age 23 ± 6 years), as a control group. Both carotid axes have been scanned from different views on a transversal and longitudinal section. Carotid diameter and thickness were measured in the longitudinal section. CCA parameters were assessed 20 mm caudally to the flow divider. In borderline patients blood pressure (147.8 ± 10.5/90.7 ± 6.6 mm Hg) and left ventricular mass index (102.5 ± 15.3 g/m<sup>2</sup>) were significantly higher than in normotensive subjects (blood pressure 120.5 ± 11.5/78.0 ± 5.4 mm Hg; left ventricular mass 90.5 ± 14.3 g/m<sup>2</sup>, p < 0.01 and p < 0.05 respectively). The intima-media thickness of both the CCA and BIF was significantly higher in borderline hypertensives than in normotensives(CCA 0.6 ± 0.08 vs. 0.4 ± 0.05 mm, p < 0.01; BIF 0.7 ± 0.08 vs. 0.5 ± 0.08, p < 0.01). In the whole population there was a statistically significant correlation between the carotid wall thickness and the left ventricular mass. In conclusion our data show that ultrasonography provides direct evidence that in young borderline hypertensives the increased left ventricular mass is associated with vascular hypertrophy.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1993
          1993
          18 November 2008
          : 83
          : 5-6
          : 298-303
          Affiliations
          Istituto di Clinica Medica, Università di Milano, and Centro di Fisiologia Clinica e Ipertensione, Ospedale Maggiore, Centro Auxologico, Milano, Italy
          Article
          175985 Cardiology 1993;83:298–303
          10.1159/000175985
          8111762
          © 1993 S. Karger AG, Basel

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          Page count
          Pages: 6
          Categories
          General Cardiology

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