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      Endoscopic diagnosis and treatment of an appendiceal mucocele: A case report

      case-report

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          Abstract

          BACKGROUND

          Appendiceal mucocele is a rare disease that causes obstructive dilatation of the appendix due to the intraluminal accumulation of mucin. We report a case of endoscopic diagnosis and treatment of an appendiceal mucocele.

          CASE SUMMARY

          A 47-year-old man presented with a protrusion around the orifice of the appendix discovered by colonoscopy incidentally. He was admitted to our hospital for a routine checkup without any symptoms. Abdominal computed tomography showed a cystic mass approximately 3 cm in diameter with fat stranding. The preoperative diagnosis was non-neoplastic appendiceal mucocele, and endoscopic treatment was performed. The endoscopic findings and pathological results supported our preoperative diagnosis. The endoscopic treatment of appendiceal mucocele was feasible and effective, which was confirmed by repeated endoscopy and post-operative computed tomography after 7 mo.

          CONCLUSION

          Endoscopic therapy provides a new method for the treatment of appendiceal mucocele.

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          Most cited references15

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          Primary neoplasms of the appendix: radiologic spectrum of disease with pathologic correlation.

          Perry Pickhardt, Angela Levy, Charles A Rohrmann … (2016)
          Although uncommon, primary appendiceal neoplasms often result in clinical symptoms that may lead to abdominal imaging. Acute appendicitis from luminal obstruction is the most common manifestation for most tumor types. Other manifestations include intussusception, a palpable mass, gastrointestinal bleeding, increasing abdominal girth (from pseudomyxoma peritonei), and secondary genitourinary complications. Asymptomatic appendiceal neoplasms may be discovered incidentally. Mucoceles from either benign or malignant mucinous neoplasms represent the majority of appendiceal tumors detected at imaging but are the least likely to manifest as appendicitis. Pseudomyxoma peritonei is a common manifestation of mucinous adenocarcinoma. Colonic-type (nonmucinous) adenocarcinoma of the appendix is much less common than mucinous tumors and typically manifests as a focal mass without mucocele formation. Carcinoid tumor is the most common appendiceal neoplasm but is less often detected radiologically because it is typically small and relatively asymptomatic. Goblet cell carcinoid tumor and non-Hodgkin lymphoma of the appendix are rare and usually infiltrate the entire appendix. Cross-sectional imaging, particularly computed tomography (CT), is effective in the evaluation of these neoplasms. CT appears to be the modality of choice whenever an appendiceal mass is suspected. CT will help rule out or confirm an appendiceal tumor and may suggest a more specific diagnosis.
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            The American Society of Colon and Rectal Surgeons, Clinical Practice Guidelines for the Management of Appendiceal Neoplasms

            Sean C Glasgow, Wolfgang Gaertner, David Stewart … (2019)
            Article 0 comments Cited 24 times – based on 0 reviews     Review now
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              Mucocoele and mucinous tumours of the appendix: A review of the literature

              Ben Rymer, Rachael O. Forsythe, Glen Husada (2015)
              Mucocoele of the appendix is rarely encountered but consultant general surgical and trainees must be aware of it as a differential diagnosis, due to the nuances associated with its management. We aimed to provide a comprehensive review of the current literature concerning this rare surgical pathology.
              Article 0 comments Cited 24 times – based on 0 reviews     Review now
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                Author and article information

                Contributors
                Ting-Ting Wang
                Jia-Jun He
                Ping-Hong Zhou
                Wei-Wei Chen
                Chao-Wu Chen
                Jun Liu
                Journal
                Journal ID (nlm-ta): World J Clin Cases
                Journal ID (publisher-id): WJCC
                Title: World Journal of Clinical Cases
                Publisher: Baishideng Publishing Group Inc
                ISSN (Electronic): 2307-8960
                Publication date (Print): 6 June 2021
                Publication date (Electronic): 6 June 2021
                Volume: 9
                Issue: 16
                Pages: 3936-3942
                Affiliations
                Department of Gastroenterology, The First Clinical Medical College, Dalian Medical University, Dalian 116044, Liaoning Province, China
                Department of Gastroenterology, The First Clinical Medical College, Dalian Medical University, Dalian 116044, Liaoning Province, China
                Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
                Endoscopy Center, Department of Gastroenterology, Clinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, China
                Endoscopy Center, Department of Gastroenterology, Clinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, China
                Endoscopy Center, Department of Gastroenterology, Clinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, China. sbyy_liujun@ 123456163.com
                Author notes

                Author contributions: Wang TT reviewed the literature and contributed to manuscript drafting; He JJ modified the manuscript; Zhou PH performed the endoscopic procedure; Chen WW and Chen CW contributed to manuscript drafting; Liu J was responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.

                Corresponding author: Jun Liu, MD, Chief Physician, Endoscopy Center, Department of Gastroenterology, Clinical Medical College, Yangzhou University, No. 88 South University Ave, Yangzhou 225009, Jiangsu Province, China. sbyy_liujun@ 123456163.com

                Article
                Other ID: jWJCC.v9.i16.pg3936
                DOI: 10.12998/wjcc.v9.i16.3936
                PMC ID: 8180202
                SO-VID: 48d12738-46bc-4149-8912-ef7e1cf256b7
                Copyright © ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
                License:

                This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

                History
                Date received : 16 November 2020
                Date revision received : 26 December 2020
                Date accepted : 18 March 2021
                Categories
                Subject: Case Report

                Keywords: appendiceal mucocele,endoscopy,colonoscopy,diagnosis,treatment,case report
                Data availability:
                Keywords: appendiceal mucocele, endoscopy, colonoscopy, diagnosis, treatment, case report

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