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      Transdiagnostic versus disorder-specific and clinician-guided versus self-guided internet-delivered treatment for generalized anxiety disorder and comorbid disorders: A randomized controlled trial.

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          Abstract

          Generalized anxiety disorder (GAD) can be treated effectively with either disorder-specific cognitive behavior therapy (DS-CBT) or transdiagnostic CBT (TD-CBT). The relative benefits of DS-CBT and TD-CBT for GAD and the relative benefits of delivering treatment in clinician guided (CG-CBT) and self-guided (SG-CBT) formats have not been examined. Participants with GAD (n=338) were randomly allocated to receive an internet-delivered TD-CBT or DS-CBT intervention delivered in either CG-CBT or SG-CBT formats. Large reductions in symptoms of GAD (Cohen's d ≥ 1.48; avg. reduction ≥ 50%) and comorbid major depressive disorder (Cohen's d ≥ 1.64; avg. reduction ≥ 45%), social anxiety disorder (Cohen's d ≥ 0.80; avg. reduction ≥ 29%) and panic disorder (Cohen's d ≥ 0.55; avg. reduction ≥ 33%) were found across the conditions. No substantive differences were observed between DS-CBT and TD-CBT or CG-CBT and SG-CBT, highlighting the public health potential of carefully developed TD-CBT and SG-CBT.

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          Author and article information

          Journal
          J Anxiety Disord
          Journal of anxiety disorders
          1873-7897
          0887-6185
          Dec 2015
          : 36
          Affiliations
          [1 ] eCentreClinic, Department of Psychology, Macquarie University, Sydney, Australia. Electronic address: blake.dear@mq.edu.au.
          [2 ] eCentreClinic, Department of Psychology, Macquarie University, Sydney, Australia.
          [3 ] eCentreClinic, Department of Psychology, Macquarie University, Sydney, Australia; School of Medicine (Psychology), University of Tasmania, Tasmania, Australia.
          [4 ] School of Psychology and Speech Pathology, Curtin University, Western Australia, Australia.
          Article
          S0887-6185(15)30013-X
          10.1016/j.janxdis.2015.09.003
          26460536
          48dbe15f-e0f5-4b3e-8baf-0eadf39a5ef6
          Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.
          History

          24-Month follow-up,Anxiety disorders,Clinician-guided,Disorder-specific,Generalized anxiety disorder,Internet,Randomized controlled trial,Self-guided,Transdiagnostic,Treatment

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