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Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer.
Fairooz Kabbinavar
1 ,
Herbert I Hurwitz ,
Louis Fehrenbacher ,
Neal J Meropol ,
William F Novotny ,
Grazyna Lieberman ,
Susan Griffing ,
Emily Bergsland
Jan 01 2003
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Abstract
This phase II trial investigated the safety and efficacy of two doses of bevacizumab, a monoclonal antibody to vascular endothelial growth factor, plus fluorouracil (FU)/leucovorin (LV) versus FU/LV alone in patients with metastatic colorectal cancer.