The advent of COVID-19 has infected millions of people causing healthcare emergencies worldwide. Biologists and environmentalists have always stressed on the impact of habitat fragmentation, deforestation, and animal poaching on human health. The outbreak of various zoonotic scourges has incremented the levels of risk in human population because of direct and indirect interaction with human chain. Human health is directly associated with animal health and is one of the important part of an ecosystem, the balance of which is disrupted due to anthropogenic activities which has disrupted an ecological balance due to which biodiversity is greatly affected and is reducing at a faster pace promoting a spread of diseases through animals to humans. COVID-19 is a serious concern that puts human life to risk, however, strategies like Global Lockdown which is referred as the period of “Great Pause” has helped to recover rare species of Flora and Fauna with reduced pollution levels, cleaner air and water. In order to quell the further on-spread of pandemic or any other avant-guarded health emergency, biodiversity shall be preserved. This chapter highlights the vitality of conserving biodiversity to renounce the healthcare challenges addressing the scenario of novel coronavirus.