Nanotransfersomes of carvedilol for intranasal delivery: formulation, characterization and in vivo evaluation.

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Abstract

Development of carvedilol-loaded transfersomes for intranasal administration to overcome poor nasal permeability and hepatic first pass effect so as to enhance its bioavailability.

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Journal ID (iso-abbrev): Drug Deliv

Title: Drug delivery

Publisher: Informa UK Limited

ISSN (Electronic): 1521-0464

ISSN (Print): 1071-7544

Publication date (Electronic): Sep 2016

Volume: 23

Issue: 7

Affiliations

[1 ] a Department of Pharmaceutics, Faculty of Pharmacy , Beni Suef University , Beni Suef , Egypt and.

[2 ] b Department of Pharmaceutics, Faculty of Pharmacy , Cairo University , Cairo , Egypt.

Article

DOI: 10.3109/10717544.2015.1013587

PubMed ID: 25715807

SO-VID: 49af73a0-b8a1-4ae0-bdff-270313a18f2b

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Keywords: intranasal,nanotransfersomes,pharmacokinetic study,Carvedilol,edge activators

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Keywords: intranasal, nanotransfersomes, pharmacokinetic study, Carvedilol, edge activators

Nanotransfersomes of carvedilol for intranasal delivery: formulation, characterization and in vivo evaluation.

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Abstract

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RNA drug delivery

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