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      Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus higher dose ICS for adults with asthma.

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          Abstract

          Long-acting muscarinic antagonists (LAMA), a class of drugs with proven effectiveness in chronic obstructive pulmonary disease (COPD), are being considered as an add-on option for adults with asthma whose condition is uncontrolled on inhaled corticosteroids (ICS). It is important to assess the safety and efficacy of LAMA add-on as an alternative to the prolonged use of higher doses of ICS, which are known to cause undesirable side effects in some people.

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          Author and article information

          Journal
          Cochrane Database Syst Rev
          The Cochrane database of systematic reviews
          Wiley
          1469-493X
          1361-6137
          Jul 21 2015
          : 7
          Affiliations
          [1 ] Lancaster Patient Safety Research Unit, Royal Lancaster Infirmary, Pointer Court 1, Ashton Road, Lancaster, UK, LA1 4RP.
          Article
          10.1002/14651858.CD011437.pub2
          26196545
          49b479bb-670f-476e-a3a0-79ca5eb7b460
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