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Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research.
Sundeep Khosla ,
David Burr ,
Jane Cauley ,
David W Dempster ,
Peter R Ebeling ,
Dieter Felsenberg ,
Robert F Gagel ,
Vincente Gilsanz ,
Theresa Guise ,
Sreenivas Koka ,
Laurie K McCauley ,
Joan McGowan ,
Marc D McKee ,
Suresh Mohla ,
David G Pendrys ,
Lawrence G Raisz ,
Salvatore L Ruggiero ,
David M Shafer ,
Lillian Shum ,
Stuart L Silverman ,
Catherine H Van Poznak ,
Nelson Watts ,
Sook-Bin Woo ,
Elizabeth Shane
Oct 2007
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Abstract
ONJ has been increasingly suspected to be a potential complication of bisphosphonate therapy in recent years. Thus, the ASBMR leadership appointed a multidisciplinary task force to address key questions related to case definition, epidemiology, risk factors, diagnostic imaging, clinical management, and future areas for research related to the disorder. This report summarizes the findings and recommendations of the task force.