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      Adenosine for pain relief in a patient with intractable secondary erythromelalgia.

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          Abstract

          An unusual case is reported with severe erythromelalgia secondary to a sensorimotor polyneuropathy of immunological aetiology. The dominating symptoms were ongoing burning dysesthesia and pain in the legs, sustained thermal hyperalgesia and allodynia to pressure which produced intolerable pain on standing and walking. The primary pain-producing pathophysiology was apparently peripheral neurogenic inflammation with sensitization and excitation of nociceptors. The variable and progressive course prompted reassessments and successively amended multitargeted analgesic regimens. The most intensive bout of widespread pain and allodynia indicating secondary central sensitization was only controlled by adenosine treatment.

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          Author and article information

          Journal
          Eur J Pain
          European journal of pain (London, England)
          1090-3801
          1090-3801
          1997
          : 1
          : 4
          Affiliations
          [1 ] Department of Anaesthesiology, Karolinska Institute, Sweden Danderyds Hospital, Stockholm.
          Article
          S1090380197900392
          15102395

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