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      The Role of Early-Phase Transmission in the Spread of Yersinia pestis.

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          Abstract

          Early-phase transmission (EPT) of Yersinia pestis by unblocked fleas is a well-documented, replicable phenomenon with poorly defined mechanisms. We review evidence demonstrating EPT and current knowledge on its biological and biomechanical processes. We discuss the importance of EPT in the epizootic spread of Y. pestis and its role in the maintenance of plague bacteria in nature. We further address the role of EPT in the epidemiology of plague.

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          Author and article information

          Journal
          J. Med. Entomol.
          Journal of medical entomology
          0022-2585
          0022-2585
          Nov 2015
          : 52
          : 6
          Affiliations
          [1 ] Bacterial Diseases Branch, Division of Vectorborne Diseases, National Center for Emerging Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO. dyn2@cdc.gov.
          [2 ] Retired.
          [3 ] Bacterial Diseases Branch, Division of Vectorborne Diseases, National Center for Emerging Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO.
          Article
          tjv128 HHSPA732005
          10.1093/jme/tjv128
          26336267
          4a48515a-6533-4ef2-a31b-4a354fa5a063
          Published by Oxford University Press on behalf of Entomological Society of America 2015. This work is written by US Government employees and is in the public domain in the US.

          Yersinia pestis,course of infection,early-phase transmission,flea,plague

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