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Synthesis and biological evaluation of a novel pyroglutamyl-modified TRH analogue.
I Cacciatore, F Pinnen, S Dupre-Aucouturier, L Recinella, A Giorgi, P Sozio, B Michelotto, G Orlando, G. Di Giovanni, G Luisi, Iguatemy Brunetti, M Spirito
2002-05-31
Animals, Cattle, Cells, Cultured, Dopamine, secretion, Dose-Response Relationship, Drug, Male, Nuclear Magnetic Resonance, Biomolecular, Pituitary Gland, Anterior, drug effects, metabolism, Prolactin, Pyroglutamyl-Peptidase I, Pyrrolidonecarboxylic Acid, chemical synthesis, chemistry, pharmacology, Rats, Rats, Wistar, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, methods, Thyrotropin-Releasing Hormone, analogs & derivatives
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Animals,Cattle,Cells, Cultured,Dopamine,secretion,Dose-Response Relationship, Drug,Male,Nuclear Magnetic Resonance, Biomolecular,Pituitary Gland, Anterior,drug effects,metabolism,Prolactin,Pyroglutamyl-Peptidase I,Pyrrolidonecarboxylic Acid,chemical synthesis,chemistry,pharmacology,Rats,Rats, Wistar,Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization,methods,Thyrotropin-Releasing Hormone,analogs & derivatives
Animals, Cattle, Cells, Cultured, Dopamine, secretion, Dose-Response Relationship, Drug, Male, Nuclear Magnetic Resonance, Biomolecular, Pituitary Gland, Anterior, drug effects, metabolism, Prolactin, Pyroglutamyl-Peptidase I, Pyrrolidonecarboxylic Acid, chemical synthesis, chemistry, pharmacology, Rats, Rats, Wistar, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, methods, Thyrotropin-Releasing Hormone, analogs & derivatives