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Delirium in elderly people
Author(s):
Sharon K Inouye
,
Rudi GJ Westendorp
,
Jane S Saczynski
Publication date
Created:
March 2014
Publication date
(Print):
March 2014
Journal:
The Lancet
Publisher:
Elsevier BV
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PMC
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There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
Delirium is an acute disorder of attention and cognition in elderly people (ie, those aged 65 years or older) that is common, serious, costly, under-recognised, and often fatal. A formal cognitive assessment and history of acute onset of symptoms are necessary for diagnosis. In view of the complex multifactorial causes of delirium, multicomponent non-pharmacological risk factor approaches are the most effective strategy for prevention. No convincing evidence shows that pharmacological prevention or treatment is effective. Drug reduction for sedation and analgesia and non-pharmacological approaches are recommended. Delirium offers opportunities to elucidate brain pathophysiology--it serves both as a marker of brain vulnerability with decreased reserve and as a potential mechanism for permanent cognitive damage. As a potent indicator of patients' safety, delirium provides a target for system-wide process improvements. Public health priorities include improvements in coding, reimbursement from insurers, and research funding, and widespread education for clinicians and the public about the importance of delirium. Copyright © 2014 Elsevier Ltd. All rights reserved.
Related collections
Special issue: Negotiating the Nation: Young people, national narratives and history education
Author and article information
Journal
Title:
The Lancet
Abbreviated Title:
The Lancet
Publisher:
Elsevier BV
ISSN (Print):
01406736
Publication date Created:
March 2014
Publication date (Print):
March 2014
Volume
: 383
Issue
: 9920
Pages
: 911-922
Article
DOI:
10.1016/S0140-6736(13)60688-1
PMC ID:
4120864
PubMed ID:
23992774
SO-VID:
4ab88b15-d907-4533-91cc-97e813878b9d
Copyright ©
© 2014
License:
https://www.elsevier.com/tdm/userlicense/1.0/
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