0
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Antagonism of neuromuscular block in the elderly. A comparison of atropine and glycopyrronium in a mixture with neostigmine.

      Anaesthesia

      Read this article at

      ScienceOpenPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Glycopyrronium 10 micrograms/kg has been compared with atropine 20 micrograms/kg in a mixture with neostigmine 50 micrograms/kg administered for antagonism of residual nondepolarising neuromuscular block in patients over 65 years of age. The initial peak increase in heart rate was less after glycopyrronium, but there were no differences beyond the first two minutes. The incidence of dysrhythmias was less after glycopyrronium but the difference was not significant. The control of secretions was superior with glycopyrronium. It is suggested that the dosage of anticholinergic agents given with neostigmine could be reduced in elderly patients in comparison to that in younger patients.

          Related collections

          Author and article information

          Journal
          Anaesthesia
          Anaesthesia
          0003-2409
          0003-2409
          Mar 1985
          : 40
          : 3
          Article
          3993883

          Comments

          Comment on this article