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Antioxidant properties of dehydrozingerone and curcumin in rat brain homogenates.

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Molecular and cellular biochemistry

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      Abstract

      The present study investigates the inhibition of lipid peroxidation by dehydrozingerone and curcumin in rat brain homogenates. Both the test compounds inhibited the formation of conjugated dienes and spontaneous lipid peroxidation. These compounds also inhibited lipid peroxidation induced by ferrous ions, ferric-ascorbate and ferric-ADP-ascorbate. In all these cases, curcumin was more active than dehydrozingerone and dl-alpha-tocopherol.

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      Affiliations
      [1 ] Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences, Manipal, India.
      Journal
      Mol. Cell. Biochem.
      Molecular and cellular biochemistry
      0300-8177
      0300-8177
      Nov 09 1994
      : 140
      : 1
      7877600

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