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      Epidemiology of peripheral arterial disease and critical limb ischemia in an insured national population.

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          Abstract

          Critical limb ischemia (CLI) represents the most severe clinical manifestation of peripheral arterial disease (PAD) and is the major cause of ischemic amputation in the United States. Risk factors and the associated incidence and prevalence of CLI have not been well described in the general population. This study describes the risk factors for PAD progression to CLI and estimates the annual incidence and prevalence of CLI in a representative United States patient cohort.

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          Author and article information

          Journal
          J. Vasc. Surg.
          Journal of vascular surgery
          1097-6809
          0741-5214
          Sep 2014
          : 60
          : 3
          Affiliations
          [1 ] Vascular Surgery Section, Department of Surgery, University of Colorado Denver, Aurora, Colo. Electronic address: mark.nehler@ucdenver.edu.
          [2 ] Lillehei Clinical Research Unit, Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minn.
          [3 ] Department of Medicine, CPC Clinical Research, Aurora, Colo.
          [4 ] Division of Cardiovascular Medicine, Department of Medicine, University of Virginia, Charlottesville, Va.
          [5 ] Division of Cardiology, Department of Medicine, University of Colorado School of Medicine, and Department of Medicine, CPC Clinical Research, Aurora, Colo.
          [6 ] Lockheed Martin, Aurora, Colo.
          [7 ] Vascular Medicine Program, Lillehei Heart Institute and Cardiovascular Division, University of Minnesota Medical School, Minneapolis, Minn.
          Article
          S0741-5214(14)00709-5
          10.1016/j.jvs.2014.03.290
          24820900
          4b185ab6-b172-4257-b7dc-6960fc0cba19
          Published by Mosby, Inc.
          History

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