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      Calcitonin gene-related peptide: the new era of migraine therapy

      editorial
      1 , * , 1 ,
      Future Drug Discovery
      Newlands Press Ltd

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          Most cited references21

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          Safety and efficacy of erenumab for preventive treatment of chronic migraine: a randomised, double-blind, placebo-controlled phase 2 trial.

          The calcitonin gene-related peptide (CGRP) pathway is important in migraine pathophysiology. We assessed the efficacy and safety of erenumab, a fully human monoclonal antibody against the CGRP receptor, in patients with chronic migraine.
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            Efficacy and safety of galcanezumab for the prevention of episodic migraine: Results of the EVOLVE-2 Phase 3 randomized controlled clinical trial

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              Efficacy and tolerability of erenumab in patients with episodic migraine in whom two-to-four previous preventive treatments were unsuccessful: a randomised, double-blind, placebo-controlled, phase 3b study

              A substantial proportion of patients with migraine does not respond to, or cannot tolerate, oral preventive treatments. Erenumab is a novel CGRP-receptor antibody with preventive efficacy in migraine. We assessed its efficacy and tolerability in patients with episodic migraine in whom previous treatment with two-to-four migraine preventives had been unsuccessful.
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                Author and article information

                Journal
                FDD
                Future Drug Discovery
                Future Drug. Discov.
                Future Drug Discovery
                Newlands Press Ltd (London, UK )
                2631-3316
                11 October 02019
                October 2019
                : 1
                : 2
                : FDD14
                Affiliations
                1Headache Center, Department of Neurology, Dartmouth-Hitchcock Medical Center Lebanon, NH 03766, USA
                Author notes
                [* ]Author for correspondence: sjtepper@ 123456gmail.com
                Article
                10.4155/fdd-2019-0018
                4b5338f7-8152-40fc-86f1-4832df8f082f
                © 2019 Stewart J Tepper

                This work is licensed under the Attribution-NonCommercial-NoDerivatives 4.0 Unported License

                History
                : 16 May 2019
                : 20 May 2019
                : 11 October 2019
                Page count
                Pages: 5
                Categories
                Editorial

                Biochemistry,Molecular medicine,Pharmaceutical chemistry,Bioinformatics & Computational biology,Biotechnology,Pharmacology & Pharmaceutical medicine

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