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      Colostrum Management for Dairy Calves

      review-article
      , DVM, DVSc
      The Veterinary Clinics of North America. Food Animal Practice
      Elsevier Inc.

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          Abstract

          Colostrum management is the single most important management factor in determining calf health and survival. Unfortunately, a significant proportion of North American dairy calves suffer from failure of passive transfer of antibodies from colostrum, contributing to excessively high preweaning mortality rates and other short- and long-term losses associated with animal health, welfare, and productivity. A successful colostrum management program requires producers to consistently provide calves with a sufficient volume of clean, high-quality colostrum within the first few hours of life. This article reviews the process of colostrogenesis and discusses important components of colostrum. The key components of delivering and monitoring a successful colostrum management program are discussed.

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          Most cited references78

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          Effects of passive immunity on growth and survival in the dairy heifer.

          Effects of 24 to 48 h serum Ig concentration on growth and survival of 1000 Holstein heifer calves were evaluated. Average serum Ig for all calves was 25.71 (SD = 19.06) mg/ml with a range of .05 to 108.27. Serum Ig concentrations were below 12 mg/ml in 28% of the heifers. Both season and age of dam contributed significantly to the variation in 24 to 48 h concentrations of serum Ig. Concentration of serum Ig at 24 to 48 h was a significant source of variation affecting average daily gain through the first 180 d of life. Seasonal factors also were significant in influencing rate of gain from birth to 180 d. Age of dam was a significant source of variation in calf weight gains but only for the first 35 d. Mortality was 6.78% for heifers with less than 12 mg/ml serum Ig at 24 to 48 h as compared with 3.33% mortality for calves with greater than 12 mg/ml concentration.
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            Passive transfer of colostral immunoglobulins in calves.

            Passive transfer of colostral immunoglobulins has long been accepted as imperative to optimal calf health. Many factors, including timing of colostrum ingestion, the method and volume of colostrum administration, the immunoglobulin concentration of the colostrum ingested, and the age of the dam have been implicated in affecting the optimization of absorption. The practice of colostrum pooling, the breed and presence of the dam, and the presence of respiratory acidosis in the calf also may affect passive transfer. Various tests have been reported to accurately measure passive transfer status in neonatal calves. The radial immunodiffusion and the enzyme-linked immunosorbent assay (ELISA) are the only tests that directly measure serum IgG concentration. All other available tests including serum total solids by refractometry, sodium sulfite turbidity test, zinc sulfate turbidity test, serum gamma-glutamyl transferase activity, and whole blood glutaraldehyde gelation estimate serum IgG concentration based on concentration of total globulins or other proteins whose passive transfer is statistically associated with that of IgG. This paper presents a comprehensive review of the literature of passive transfer in calves including factors that affect passive transfer status, testing modalities, effects of failure of passive transfer on baseline mortality, consequences of failure of passive transfer, and some treatment options. Many previously accepted truisms regarding passive transfer in calves should be rejected based on the results of recent research.
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              Growth factors and antimicrobial factors of bovine colostrum

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                Author and article information

                Contributors
                Journal
                Vet Clin North Am Food Anim Pract
                Vet. Clin. North Am. Food Anim. Pract
                The Veterinary Clinics of North America. Food Animal Practice
                Elsevier Inc.
                0749-0720
                1558-4240
                23 February 2008
                March 2008
                23 February 2008
                : 24
                : 1
                : 19-39
                Affiliations
                Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, 225 VMC, 1365 Gortner Avenue, St. Paul, MN 55108, USA
                Article
                S0749-0720(07)00075-8
                10.1016/j.cvfa.2007.10.005
                7127126
                18299030
                4b556ac7-fc4c-43b5-90f0-e30925773e97
                Copyright © 2008 Elsevier Inc. All rights reserved.

                Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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