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      The Rate Stabilizing Tool: Generating Stable Local-Level Measures of Chronic Disease

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          Abstract

          Accurate and precise estimates of local-level epidemiologic measures are critical to informing policy and program decisions, but they often require advanced statistical knowledge, programming/coding skills, and extensive computing power. In response, we developed the Rate Stabilizing Tool (RST), an ArcGIS-based tool that enables users to input their own record-level data to generate more reliable age-standardized measures of chronic disease (eg, prevalence rates, mortality rates) or other population health outcomes at the county or census tract levels. The RST uses 2 forms of empirical Bayesian modeling (nonspatial and spatial) to estimate age-standardized rates and 95% credible intervals for user-specified geographic units. The RST also provides indicators of the reliability of point estimates. In addition to reviewing the RST’s statistical techniques, we present results from a simulation study that illustrates the key benefit of smoothing. We demonstrate the dramatic reduction in root mean-squared error (rMSE), indicating a better compromise between accuracy and stability for both smoothing approaches relative to the unsmoothed estimates. Finally, we provide an example of the RST’s use. This example uses heart disease mortality data for North Carolina census tracts to map the RST output, including reliability of estimates, and demonstrates a subsequent statistical test.

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            Efficient interval estimation for age-adjusted cancer rates

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              Geographical variation in life expectancy at birth in England and Wales is largely explained by deprivation.

              To describe the population mortality profile of England and Wales by deprivation and in each government office region (GOR) during 1998, and to quantify the influence of geography and deprivation in determining life expectancy. Construction of life tables describing age specific mortality rates and life expectancy at birth from death registrations and estimated population counts. Life tables were created for (a) quintiles of income deprivation based on the income domain score of the index of multiple deprivation 2000, (b) each GOR and Wales, and (c) every combination of deprivation and geography. England and Wales.PATIENTS/ PARTICIPANTS: Residents of England and Wales, 1998. Life expectancy at birth varies with deprivation quintile and is highest in the most affluent groups. The differences are mainly attributable to differences in mortality rates under 75 years of age. Regional life expectancies display a clear north-south gradient. Linear regression analysis shows that deprivation explains most of the geographical variation in life expectancy. Geographical patterns of life expectancy identified within these data for England and Wales in 1998 are mainly attributable to variations in deprivation status as defined by the IMD 2000 income domain score.
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                Author and article information

                Journal
                Prev Chronic Dis
                Prev Chronic Dis
                PCD
                Preventing Chronic Disease
                Centers for Disease Control and Prevention
                1545-1151
                2019
                28 March 2019
                : 16
                : E38
                Affiliations
                [1 ]Department of Epidemiology and Biostatistics, Drexel University, Philadelphia, Pennsylvania
                [2 ]Children’s Environmental Health Initiative, Rice University, Houston, Texas
                [3 ]Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia
                Author notes
                Corresponding Author: Harrison Quick, PhD, Department of Epidemiology and Biostatistics, Drexel University, 3215 Market St, Philadelphia, PA 19104. Email: hsq23@ 123456drexel.edu .
                Article
                18_0442
                10.5888/pcd16.180442
                6464039
                30925140
                4b64ee2f-4401-45e8-8bce-6759daa4bcaa
                History
                Categories
                Tools for Public Health Practice
                Peer Reviewed

                Health & Social care
                Health & Social care

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