1
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Incidence and causes of neonatal hyperbilirubinemia in a center of Catania

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Aim and scope:

          We conducted this study to estimate the incidence of hyperbilirubinemia in a small neonatal care unit in Catania, Italy, and to determine the underlying causes, which would be of value in identifying and implementing strategies to prevent morbidity from this condition.

          Background:

          Management of hyperbilirubinemia remains a challenge for neonatal medicine because of the risk for serious neurological complications related to the toxicity of bilirubin.

          Methods:

          From January 2006 to January 2007, we screened 525 newborns born at the Neonatal Care Unit of Valsalva Hospital in Catania, Italy. Infants aged 3–5 days and with unconjugated hyperbilirubinemia were included for assessment if they had a peak serum total bilirubin level exceeding 6 mg/dl (102 μmol/L). Sex, birth weight, gestational age, breast feeding, type of birth, presence of facial bruising (including cephalohematoma) and ABO group were noted. Patients with Toxoplasma or Cytomegalovirus infection, hepatic insufficiency, or suspected drug-induced hyperbilirubinemia were excluded from more detailed analysis.

          Results:

          Our year-long nursery sample examined otherwise healthy-appearing term infants for the prevalence of hyperbilirubinemia (defined as bilirubin levels exceeding 6 mg/dL [11mol/L]). We found hyperbilirubinemia in 19% (100/525). Among the patients with hyperbilirubinemia, almost all (99%) had peak levels of bilirubin <20 mg/dL, levels which are generally considered to be potentially neurotoxic.

          Conclusions:

          In our clinic experience, hyperbilirubinemia was generally a serious medical issue and one whose etiology can usually be well defined.

          Related collections

          Author and article information

          Journal
          Ther Clin Risk Manag
          Therapeutics and Clinical Risk Management
          Therapeutics and Clinical Risk Management
          Dove Medical Press
          1176-6336
          1178-203X
          2009
          2009
          26 March 2009
          : 5
          : 247-250
          Affiliations
          [1 ]Neonatal Care Section, Valsalva Hospital, Catania, Italy;
          [2 ]Department of Internal Medicine, Hospital S Marta University of Catania, Italy;
          [3 ]Pediatric Unit, Department of Pediatric Hospital Civile, Ragusa, Italy;
          [4 ]Department of Neurology, University of Catania, Italy;
          [5 ]Department of Neurology, Morristown Memorial Hospital, New Jersey, USA;
          [6 ]Pediatric Unit, Department of Pediatric and Pediatric Neurology, University of Catania, Italy
          Author notes
          Correspondence: Piero Pavone, Divisione di Clinica Pediatrica, Clinica, Pediatrica, Università di Catania, Via Santa Sofia 78 – 95125 Catania, Italy, Tel +39 095 378 2478/378 2394, Fax +39 095 222 532, Email ppavone@ 123456mbox.unict.it
          Article
          tcrm-5-0247
          2697514
          19436609
          © 2009 Sciuto et al, publisher and licensee Dove Medical Press Ltd.

          This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.

          Categories
          Short Report

          Medicine

          incidence, newborns, breastfeeding, hyperbilirubinemia

          Comments

          Comment on this article