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      A trial of the synthetic malaria vaccine SPf66 in Tanzania: rationale and design

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          Abstract

          The development of a safe, affordable and effective malaria vaccine to form part of control schemes in malaria endemic countries is a priority for researchers and public health officials. SPf66 is the first malaria vaccine to have shown partial protection against natural challenge in a phase III trial carried out in a hypoendemic area of Colombia. This paper describes the rationale and design of the first field trial of SPf66 outside South America, and the first to be conducted in an area of high perennial transmission.

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          Author and article information

          Journal
          Vaccine
          Vaccine
          Elsevier BV
          0264410X
          January 1994
          January 1994
          : 12
          : 2
          : 181-186
          Article
          10.1016/0264-410X(94)90058-2
          8147101
          4ba0d038-ede9-4f9f-bf78-e7a8476697c8
          © 1994

          https://www.elsevier.com/tdm/userlicense/1.0/

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