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Abstract
Distinct speech characteristics that may aid in differentiation between Parkinson's
disease (PD), progressive supranuclear palsy (PSP) and multiple system atrophy (MSA)
remain tremendously under-explored. Here, the patterns and degree of consonant articulation
deficits across voiced and voiceless stop plosives in 16 PD, 16 PSP, 16 MSA and 16
healthy control speakers were evaluated using acoustic and perceptual methods. Imprecise
consonant articulation was observed across all Parkinsonian groups. Voice onset time
of voiceless plosives was more prolonged in both PSP and MSA compared to PD, presumably
due to greater severity of dysarthria and slower articulation rate. Voice onset time
of voiced plosives was significantly shorter only in MSA, likely as a consequence
of damage to cerebellar structures. In agreement with the reduction of pre-voicing,
MSA manifested increased number of voiced plosives misclassified as voiceless at perceptual
evaluation. Timing of articulatory movements may provide important clues about the
pathophysiology of underlying disease.