28
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Respiratory-gated ¹⁸F-FDG PET/CT for the diagnosis of liver metastasis.

      European Journal of Radiology
      Aged, Aged, 80 and over, Carcinoma, diagnosis, secondary, Female, Fluorodeoxyglucose F18, diagnostic use, Humans, Image Enhancement, methods, Liver Neoplasms, Male, Middle Aged, Multimodal Imaging, Positron-Emission Tomography, Radiopharmaceuticals, Reproducibility of Results, Respiratory-Gated Imaging Techniques, Sensitivity and Specificity, Tomography, X-Ray Computed, Whole Body Imaging

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          To ascertain the role of respiratory-gated PET/CT with (18)F-fluorodeoxyglucose ((18)F-FDG) for accurate diagnosis of liver metastasis. Forty patients with suspected liver metastasis underwent conventional whole-body PET/CT scan initially, followed by respiratory-gated PET/CT scan covering the liver. Visual detectability (using a 5-point confidence scale), maximum standardized uptake value (SUVmax) and metabolic tumor volume (MTV) of hepatic metastatic lesions were assessed for three data sets including ordinary whole-body (WB) scan, and non-respiratory-gated (nRG) and respiratory-gated (RG) scans. Results of enhanced CT and/or MRI, or clinical and radiological follow-up were used for reference. Sixteen of the patients were found to have 53 metastatic lesions in the liver. Patient-based accuracy of WB, nRG, and RG was 92.5%, 95.0%, and 97.5%, respectively, with a lesion-based detection rate of 67.9%, 73.6%, and 73.6%, respectively. The average SUVmax of 34 liver metastatic lesions for WB, nRG, and RG was 6.60 ± 2.34, 7.19 ± 2.66, and 8.08 ± 3.24, respectively. SUVmax for RG was significantly higher than that for WB (p=0.0069). The average MTV of these 40 lesions for the three protocols was 5.32 ± 4.78 cm(3), 5.07 ± 4.73 cm(3), and 4.73 ± 4.67 cm(3), respectively. Among the three protocols, RG showed the best visual and quantitative evaluation for diagnosis of liver metastasis. Respiratory-gated PET/CT allows more accurate identification of liver metastases than non-respiratory-gated PET/CT. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

          Related collections

          Author and article information

          Comments

          Comment on this article