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      The Use of Fluorescent Nuclear Dyes for the Study of Blood Vessel Structure and Function: Novel Applications of Existing Techniques

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          Abstract

          We have used nuclear fluorescent dyes to develop a technique for the study of vascular structure and function. Nuclear stained blood vessels, viewed with the appropriate filter sets, can be studied in great detail. Only the nuclei of the cells which form the walls are visible and so their positions relative to one another as well as their viability can be quickly assessed. The dyes are not toxic, therefore when the vessel contracts or relaxes, the changes in position of the nuclei can be monitored. In this paper we describe two original applications of fluorescent nuclear dyes in vascular research.

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          Author and article information

          Journal
          JVR
          J Vasc Res
          10.1159/issn.1018-1172
          Journal of Vascular Research
          S. Karger AG
          1018-1172
          1423-0135
          1992
          1992
          23 September 2008
          : 29
          : 1
          : 41-48
          Affiliations
          Autonomic Physiology Unit, Institute of Physiology, University of Glasgow, UK
          Article
          158930 J Vasc Res 1992;29:41–48
          10.1159/000158930
          1372834
          © 1992 S. Karger AG, Basel

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          Page count
          Pages: 8
          Categories
          Research Paper

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