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      State of art in heart transplantation

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          Abstract

          Heart transplantation (HTX) has become an accepted treatment for selected patients with end-stage heart failure. There are two transplant centres in the Czech Republic, Prague since 1984 and Brno since 1992, in which more than 1000 heart transplantations were performed. Pharmacotherapy after heart transplantation includes the problems of immunosuppression and interactions of immunosuppressant drugs and their adverse effects. The main task for future is to find better immunosuppression with less side effects, to replace invasive bioptic examination of rejection and to find alternatives to clasical transplantation: xenotransplantation, stem cell transplantation or development of new ventricle assisst devices.

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          Author and article information

          Journal
          1646
          121666
          Interventional Medicine and Applied Science
          IMAS
          Akadémiai Kiadó, co-published with Springer Science+Business Media B.V., Formerly Kluwer Academic Publishers B.V.
          2061-1617
          2061-5094
          1 September 2011
          : 3
          : 3
          : 113-115
          Affiliations
          [ 1 ] 1st Internal Cardioangiological Department, St. Ann Hospital and Medical Faculty of Masaryk University, Brno, Czech Republic
          Author notes
          Article
          7
          10.1556/imas.3.2011.3.7
          4c0f6765-a39f-4c29-b200-2c7c94c07589
          Categories
          Selected Paper

          Medicine,Immunology,Health & Social care,Microbiology & Virology,Infectious disease & Microbiology
          rejection,immunosuppression,heart transplantation,echocardiography

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