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      Autologous CD133+ bone marrow cells and bypass grafting for regeneration of ischaemic myocardium: the Cardio133 trial.

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          Abstract

          Intra-myocardial transplantation of CD133(+) bone marrow stem cells (BMC) yielded promising results in clinical pilot trials. We now performed the double-blinded, randomized, placebo-controlled CARDIO133 trial to determine its impact on left ventricular (LV) function and clinical symptoms.

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          Author and article information

          Journal
          Eur. Heart J.
          European heart journal
          1522-9645
          0195-668X
          May 14 2014
          : 35
          : 19
          Affiliations
          [1 ] Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin 13353, Germany.
          [2 ] Pediatric Bone Marrow Transplant Program, Charité, Universitätsmedizin Berlin, Berlin 10117, Germany.
          [3 ] Department of Anesthesiology, Deutsches Herzzentrum Berlin, Berlin 13353, Germany.
          [4 ] Department of Internal Medicine/Cardiology, Deutsches Herzzentrum Berlin, Berlin 13353, Germany.
          [5 ] Berlin-Brandenburg Center for Regenerative Therapies, Berlin 13353, Germany.
          [6 ] Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin 13353, Germany Berlin-Brandenburg Center for Regenerative Therapies, Berlin 13353, Germany stamm@dhzb.de.
          Article
          ehu007
          10.1093/eurheartj/ehu007
          24497345
          Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: journals.permissions@oup.com.

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