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      A preliminary screening system for diabetes based on in-car electronic nose

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          Abstract

          Studies have found differences in the concentration of volatile organic compounds in the breath of diabetics and healthy people, prompting attention to the use of devices such as electronic noses to detect diabetes. In this study, we explored the design of a non-invasive diabetes preliminary screening system that uses a homemade electronic nose sensor array to detect respiratory gas markers. In the algorithm part, two feature extraction methods were adopted, gradient boosting method was used to select promising feature subset, and then particle swarm optimization algorithm was introduced to extract 24 most effective features, which reduces the number of sensors by 56% and saves the system cost. Respiratory samples were collected from 120 healthy subjects and 120 diabetic subjects to assess the system performance. Random forest algorithm was used to classify and predict electronic nose data, and the accuracy can reach 93.33%. Experimental results show that on the premise of ensuring accuracy, the system has low cost and small size after the number of sensors is optimized, and it is easy to install on in-car. It provides a more feasible method for the preliminary screening of diabetes on in-car and can be used as an assistant to the existing detection methods.

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          Most cited references34

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          LIBSVM: A library for support vector machines

          LIBSVM is a library for Support Vector Machines (SVMs). We have been actively developing this package since the year 2000. The goal is to help users to easily apply SVM to their applications. LIBSVM has gained wide popularity in machine learning and many other areas. In this article, we present all implementation details of LIBSVM. Issues such as solving SVM optimization problems theoretical convergence multiclass classification probability estimates and parameter selection are discussed in detail.
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            A new optimizer using particle swarm theory

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              A European Respiratory Society technical standard: exhaled biomarkers in lung disease.

              Breath tests cover the fraction of nitric oxide in expired gas (FeNO), volatile organic compounds (VOCs), variables in exhaled breath condensate (EBC) and other measurements. For EBC and for FeNO, official recommendations for standardised procedures are more than 10 years old and there is none for exhaled VOCs and particles. The aim of this document is to provide technical standards and recommendations for sample collection and analytic approaches and to highlight future research priorities in the field. For EBC and FeNO, new developments and advances in technology have been evaluated in the current document. This report is not intended to provide clinical guidance on disease diagnosis and management.Clinicians and researchers with expertise in exhaled biomarkers were invited to participate. Published studies regarding methodology of breath tests were selected, discussed and evaluated in a consensus-based manner by the Task Force members.Recommendations for standardisation of sampling, analysing and reporting of data and suggestions for research to cover gaps in the evidence have been created and summarised.Application of breath biomarker measurement in a standardised manner will provide comparable results, thereby facilitating the potential use of these biomarkers in clinical practice.

                Author and article information

                Journal
                Endocr Connect
                Endocr Connect
                EC
                Endocrine Connections
                Bioscientifica Ltd (Bristol )
                2049-3614
                19 January 2023
                20 January 2023
                01 March 2023
                : 12
                : 3
                : e220437
                Affiliations
                [1 ]School of Mechanical and Aerospace Engineering , Jilin University, Changchun, China
                [2 ]Weihai Institute for Bionics , Jilin University, Weihai, China
                [3 ]School of Mathematics , Jilin University, Changchun, China
                [4 ]Department of endocrinology , Jinshan Branch of Shanghai Sixth People's Hospital, Shanghai, China
                [5 ]Department of VIP Unit , China-Japan Union Hospital of Jilin University, Changchun, China
                [6 ]Digital Intelligent Cockpit Department , Intelligent Connected Vehicle Development Institute, China FAW Group Co LTD, Changchun, China
                [7 ]College of Biological and Agricultural Engineering , Jilin University, Changchun, China
                [8 ]Key Laboratory of Bionic Engineering , Ministry of Education, Jilin University, Changchun, China
                Author notes
                Correspondence should be addressed to Z Chang or R Liu: zychang@ 123456jlu.edu.cn or liur@ 123456jlu.edu.cn

                *(X Weng and G Li contributed equally to this work)

                Author information
                http://orcid.org/0000-0002-2734-9267
                Article
                EC-22-0437
                10.1530/EC-22-0437
                9986382
                36662684
                4c990f8f-c964-42aa-a57b-14af5256d048
                © the author(s)

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

                History
                : 14 October 2022
                : 19 January 2023
                Categories
                Research

                breath analysis,gas sensor,diabetes screening,electronic noses

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