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      Non-Hodgkin's lymphoma of the thyroid. A clinical study of twenty-two cases.

      Acta Oncologica (Stockholm, Sweden)
      Adult, Aged, Aged, 80 and over, Antibiotics, Antineoplastic, administration & dosage, Antineoplastic Agents, Alkylating, Antineoplastic Agents, Hormonal, Antineoplastic Agents, Phytogenic, Antineoplastic Combined Chemotherapy Protocols, therapeutic use, Combined Modality Therapy, Cyclophosphamide, Doxorubicin, analogs & derivatives, Female, Follow-Up Studies, Humans, Lymphoma, B-Cell, drug therapy, pathology, radiotherapy, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Non-Hodgkin, Male, Middle Aged, Neoplasm Staging, Prednisolone, Respiratory Sounds, physiopathology, Retrospective Studies, Survival Rate, Thyroid Neoplasms, Vincristine

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          Abstract

          Non-Hodgkin's lymphoma (NHL) of the thyroid gland is a rare disease. In the present study, the survival rate and characteristics were retrospectively analyzed in 22 patients with stage IE and IIE thyroid NHL treated with radiotherapy with or without combination chemotherapy. Seventeen NHL had histological evidence of lymphoma of mucosa-associated lymphoid tissue (MALT) type. The 5-year survival rate was 85% in all patients, with 100% and 63% respectively, for stage IE and stage IIE patients. The highly significant factor correlated with decreased determinate survival was concomitant stridor.

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