This paper presents a telepresence interaction framework and system based on touch screen and telepresence robot technologies. The system is composed of a telepresence robot and tele-interactive devices in a remote environment (presence space), the touching live video image user interface (TIUI) used by an operator (user) in an operation space, and wireless network connecting the two spaces. A tele-interactive device refers to a real object with its identification, actuator, and Wireless communication. A telepresence robot is used as the embodiment of an operator to go around in the presence space to actively capture live videos. The TIUI is our new user interface which allows an operator simply uses a pad to access the system anywhere to not only remotely operate the telepresence robot but also interact with a tele-interactive device, just by directly touching its live video image as if him/her to do it in the presence. The preliminary evaluation and demonstration show the efficacy and promising of our framework and system.