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      Percutaneous Left Atrial Appendage Closure vs Warfarin for Atrial Fibrillation : A Randomized Clinical Trial

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          Abstract

          While effective in preventing stroke in patients with atrial fibrillation (AF), warfarin is limited by a narrow therapeutic profile, a need for lifelong coagulation monitoring, and multiple drug and diet interactions.

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          Author and article information

          Journal
          JAMA
          JAMA
          American Medical Association (AMA)
          0098-7484
          November 19 2014
          November 19 2014
          : 312
          : 19
          : 1988
          Affiliations
          [1 ]Mount Sinai School of Medicine, New York City, New York2St John’s Health Center, Santa Monica, California3Homolka Hospital, Prague, Czech Republic
          [2 ]Cardiovascular Center Frankfurt, Sankt Katharinen, Frankfurt, Germany
          [3 ]Mount Sinai School of Medicine, New York City, New York
          [4 ]St John’s Health Center, Santa Monica, California
          [5 ]Foundation for Cardiovascular Medicine, La Jolla, California
          [6 ]Homolka Hospital, Prague, Czech Republic
          [7 ]St Luke’s Hospital, Kansas City, Missouri
          [8 ]Intermountain Medical Center, Murray, Utah
          [9 ]Cedars Sinai Medical Center, Los Angeles, California
          [10 ]Arizona Heart Rhythm Center, Scottsdale
          [11 ]Boston Scientific, St Paul, Minnesota
          [12 ]Mayo Clinic College of Medicine, Rochester, Minnesota
          Article
          10.1001/jama.2014.15192
          25399274
          © 2014

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