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      Rentabilidad de la biopsia prostática y determinación de valores del psa: incidencia de cáncer prostático y complicaciones postbiopsia Translated title: Profitability of prostate biopsy and PSA values determination: impact of prostate cancer and post-biopsy complications

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          Abstract

          Objetivo: Determinar la tasa diagnostica de cáncer prostático (CaP) de nuestro hospital mediante biopsia prostática (Bp), así como analizar si existen diferencias significativas entre las diferentes variables PSA y el resultado anatomo-patológico. De forma secundaria, analizar nuestra tasa de complicaciones postbiopsia. Material y Métodos: Estudio retrospectivo descriptivo y analítico de los pacientes biopsiados en el año 2014, analizando las variables cuantitativas edad, PSA libre, PSA Total, Cociente PSA Libre/Total y número de cilindros y analizando las variables cualitativas resultado de anatomía patológica y complicaciones. Resultados: Incluimos en el estudio a 86 pacientes con una media de edad de 67,5 años [49-84]. La media del PSA total fue de 7,67 ng/dl [2,83-29], PSA libre de 1,05 ng/dl [0,32-2,45] y cociente de 0,16 [0,05-0,31]. La media de cilindros extraídos por Bp fue de 10,5 cilindros [4-18]. La tasa de resultados positivos en Bp fue del 30,2% (26 pacientes). Al comparar los pacientes que tuvieron biopsia positiva vs biopsia negativas hallamos diferencias estadísticamente significativas entre valores de PSA libre (p=0,039) y los del cociente de PSA (p=0,015). Tras Bp precisaron ingreso por complicación 4 pacientes. Conclusiones: Nuestra tasa diagnostica de CaP mediante Bp es similar a la de otras series descritas. El valor del cociente PSA libre/total es una herramienta fiable para indicar una biopsia. Nuestra tasa de complicaciones postbiopsia es similar a la de las guías Europeas, por lo que consideramos óptimo nuestro protocolo de profilaxis para la biopsia prostática.

          Translated abstract

          Aim: To determinate the diagnosis rate of prostate cancer (CaP) of our hospital through prostate biopsy (Pb) and to analyse whether there are significant differences between the diverse variables of PSA and the anatomic-pathology results. In addition an to a lesser extent, to study our rates of post-biopsy complications. Material and Methodology: retrospective research, both descriptive and analytical, of the patients who underwent biopsy in 2014, analysing the quantitative values of age, free PSA, total PSA, free/ total PSA quotient and number of cylinders, and analysis of the qualitative variables resulting from anatomic-pathology and further complications. Results: The research includes 86 patients of 67.5 years old average [49-84]. The average total PSA was 7,67 ng/dl [2,83-29, free PSA 1,05 ng/dl [0,32-2,45] and PSA quotient of 0,16 [0,05-0,31]. The average cylinders obtained with Pb was 10.5 cylinders [4-18]. The rate of positive results in Bp was 30.2% (26 patients). When comparing patients with positive and negative Pbs, significant differences were found between free PSA values (p=0,039) and those of PSA quotient (p=0,015). Four patients required hospitalisation after Pb due to unforeseen complications. Conclusions: Our diagnosis rate of CaP through Pb is similar to the one of other described series. The PSA free/ total quotient is a reliable tool to indicate a biopsy. Our rate of post-biopsy complications is similar to the ones described in European guidelines which implies our prophylaxis protocol for prostate biopsy is optimum.

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          Author and article information

          Journal
          sm
          Sanidad Militar
          Sanid. Mil.
          Ministerio de Defensa (Madrid, Madrid, Spain )
          1887-8571
          December 2016
          : 72
          : 4
          : 260-265
          Affiliations
          [02] Tudela orgnameHospital Reina Sofía de Tudela orgdiv1Servicio de Urología
          [01] Zaragoza orgnameHospital General de la Defensa de Zaragoza orgdiv1Servicio de Urología
          Article
          S1887-85712016000400003 S1887-8571(16)07200400003
          4de77f6e-ffa4-4841-a994-e8a1b7a29472

          http://creativecommons.org/licenses/by/4.0/

          History
          : 05 April 2016
          : 30 June 2016
          Page count
          Figures: 0, Tables: 0, Equations: 0, References: 0, Pages: 6
          Product

          SciELO Spain

          Categories
          Artículo Original

          Prostate cancer,prostate biopsy,PSA,Prostatitis,Cáncer prostático,biopsia prostática,prostatitis

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