Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, USA
)
ISSN
(Electronic):
1932-6203
Publication date Collection: 2013
Publication date
(Electronic):
9
July
2013
Volume: 8
Issue: 7
Electronic Location Identifier: e68708
Affiliations
[1
]Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts,
United States of America
[2
]Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States
of America
[3
]Molecular Pathology Unit, Center for Cancer Research, and Center for Computational
and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts,
United States of America
[4
]Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States
of America
[5
]Broad Institute, Cambridge, Massachusetts, United States of America
Mayo Clinic, United States of America
Author notes
Competing Interests: One of the authors, JKJ has a financial interest in Transposagen Biopharmaceuticals.
JKJs interests were reviewed and are managed by Massachusetts General Hospital and
Partners HealthCare in accordance with their conflict of interest policies. This does
not alter the authors' adherence to all the PLOS ONE policies on sharing data and
materials.
Conceived and designed the experiments: WYH YF DR MLM JDS JKJ RTP JRJY. Performed
the experiments: WYH YF DR MLM PK. Analyzed the data: WYH YF DR MLM PK JDS JKJ RTP
JRJY. Contributed reagents/materials/analysis tools: WYH YF DR MLM JDS. Wrote the
paper: WYH YF DR MLM JDS JKJ RTP JRJY.
Article
Publisher ID:
PONE-D-13-13968
DOI: 10.1371/journal.pone.0068708
PMC ID: 3706373
PubMed ID: 23874735
SO-VID: 4dfd11f7-43f2-40d2-a24d-48daf891cbed
Copyright statement:
Copyright @
2013
License:
This is an open-access article distributed under the terms of the Creative Commons
Attribution License, which permits unrestricted use, distribution, and reproduction
in any medium, provided the original author and source are credited.
This work was supported by National Institutes of Health [R01 GM088040 to JKJ and
RTP, NIH Director’s Pioneer Award DP1 OD006862 to JKJ, K01 AG031300 to JRJY, R01 CA140188
to JRJY]; Defense Advanced Research Projects Agency (DARPA) [W911NF-11-2-0056 to JKJ];
the Jim and Ann Orr MGH Research Scholar award (JKJ); the Charles and Ann Sanders
MGH Research Scholar award (RTP); and the MGH Claflin Distinguished Scholar Award
(JRJY). The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology
Subject:
Biotechnology
Subject:
Bioengineering
Subject:
Biological Systems Engineering
Subject:
Genetic Engineering
Subject:
Transgenics
Subject:
Genetics
Subject:
Genetic Mutation
Subject:
Heredity
Subject:
Model Organisms
Subject:
Animal Models
Subject:
Zebrafish
Subject:
Engineering
Subject:
Bioengineering
Subject:
Biological Systems Engineering